The influence of component structural arrangement on peptide vaccine immunogenicity

N Alharbi, M Skwarczynski, I Toth - Biotechnology Advances, 2022 - Elsevier
Peptide-based subunit vaccines utilise minimal immunogenic components (ie peptides) to
generate highly specific immune responses, without triggering adverse reactions. However …

[HTML][HTML] Engineered macromolecular Toll-like receptor agents and assemblies

BAJ Hoffman, EA Pumford, AI Enueme, KL Fetah… - Trends in …, 2023 - cell.com
Macromolecular Toll-like receptor (TLR) agents have been utilized as agonists and
inhibitors in preclinical and clinical settings. These agents interface with the TLR class of …

Recent progress in synthetic self-adjuvanting vaccine development

D Ariawan, J van Eersel, AD Martin, YD Ke… - Biomaterials …, 2022 - pubs.rsc.org
Vaccination is a proven way to protect individuals against many infectious diseases, as
currently highlighted in the global COVID-19 pandemic. Peptides-or small molecule antigen …

Innovative vaccine strategy: self-adjuvanting conjugate vaccines

Y Manabe, K Fukase - Glycolipids: Methods and Protocols, 2023 - Springer
Self-adjuvanting vaccines, covalent conjugates between antigens and adjuvants, are
chemically well-defined compared with conventional vaccines formulated through mixing …