[HTML][HTML] Current animal model systems for ovarian aging research

H Lu, L Ma, Y Zhang, Y Feng, J Zhang… - Aging and Disease, 2022 - ncbi.nlm.nih.gov
Ovarian aging leads to menopause, loss of fertility and other disorders in multiple organs,
which brings great distress to women. For ethical reasons, it is impossible to use humans as …

Endogenous sex hormones and endothelial function in postmenopausal women and men: the multi-ethnic study of atherosclerosis

L Mathews, V Subramanya, DI Zhao… - Journal of Women's …, 2019 - liebertpub.com
Background: The relationship of endogenous sex hormones (SH) with vascular endothelial
function and with cardiovascular disease (CVD) is incompletely understood. We examined …

Interleukin-6 promotes murine estrogen deficiency-associated cerebral aneurysm rupture

D Wajima, S Hourani, W Dodd, D Patel, C Jones… - …, 2020 - journals.lww.com
OBJECTIVE To test the hypothesis that IL-6 is required for the increase in aneurysm rupture
rate observed in estrogen-deficient mice. METHODS We analyzed IL-6 expression in human …

Mood, hormone levels, metabolic and sleep across the menopausal transition in VCD-induced ICR mice

S Yu, L Zhang, Y Wang, J Yan, Q Wang, H Bian… - Physiology & …, 2023 - Elsevier
Aims Menopausal transition is the transitional period before menopause in women, often
accompanied by abnormal fluctuations in hormone levels that increase the risk of aging …

Cardiometabolic Changes in Different Gonadal Female States Caused by Mild Hyperuricemia and Exposure to a High‐Fructose Diet

J Soutelo, YA Samaniego, MC Fornari… - International Journal …, 2018 - Wiley Online Library
Background. The objective of this study is to observe if mild hyperuricemia and a high‐
fructose diet influence the cardiovascular and metabolic systems in hypogonadic female …

Ovarian failure induced by 4-vinylcyclohexene diepoxide worsens the autonomic cardiovascular response to chronic unpredictable stress in rats

F Lorenzon, BB Simas, T Gregorio, JA Anselmo-Franci… - Life sciences, 2019 - Elsevier
Aims After menopause, women are more responsive to stress and more prone to exhibit
hypertension, which elevates the risk of cardiac diseases. This vulnerability is due, in part, to …