Since the insight to fuse Fenton chemistry and nanomedicine into cancer therapy, great
signs of progress have been made in the field of chemodynamic therapy (CDT). However …

Typical PeT-based fluorescent probes are multi-component systems where a fluorophore is
connected to a recognition/activating group by an unconjugated linker. PeT-based …

Mitochondria are essential for the activity, function and viability of eukaryotic cells and
mitochondrial dysfunction is involved in the pathogenesis of acute kidney injury (AKI) and …

One of the most significant challenges of inflammatory bowel disease (IBD) research is to
understand how alterations in the symbiotic relationship between the genetic composition of …

Although reactive oxygen species (ROS) are essential for cellular processes, excessive
ROS could be a major cause of various inflammatory diseases because of the oxidation of …

The endoplasmic reticulum (ER) acts as a moving organelle with many important cellular
functions. As the ER lacks sufficient nutrients under pathological conditions leading to …

Autophagy is a conserved lysosomal degradation pathway where cellular components are
dynamically degraded and re-processed to maintain physical homeostasis. However, the …

Autophagy is a powerful tool that host cells use to defend against viral infection. Double-
membrane vesicles, termed autophagosomes, deliver trapped viral cargo to the lysosome …

Protein folding is inherently error prone, especially in the endoplasmic reticulum (ER). Even
with an elaborate network of molecular chaperones and protein folding facilitators …

Endoplasmic reticulum (ER)-associated degradation (ERAD) and the unfolded protein
response (UPR) are two key quality-control machineries in the cell. ERAD is responsible for …