Gene therapy is a promising strategy for treating challenging diseases. The successful
delivery of genes is a critical step for gene therapy. However, concerns about …

Gene and nucleic acid delivery constitute a huge biological challenge and several attempts
have been made by research laboratories to address this issue. Cationic polymers and …

The synthesis of new chitin derivatives through ultrasound-assisted treatment of the chitin
with 1-azido-3-chloropropan-2-ol under Green Chemistry conditions is described. This is the …

The development of intravitreal glucocorticoid delivery systems is a current global challenge
for the treatment of inflammatory diseases of the posterior segment of the eye. The main …

Off-target drug delivery, together with multidrug resistance (MDR), are two keys obstacles
that account for the disappointing outcome in clinical chemotherapy of cancer. To solve …

Improving the therapeutic characteristics of antibiotics is an effective strategy for controlling
the growth of multidrug-resistant Gram-negative microorganisms. The purpose of this study …

In this work, we involved ultrasound-assisted click CuAAC in chitosan chemistry. Ultrasound-
mediated CuAAC between propargylic ester of betaine and azido chitosan derivative …

In this work, we demonstrate that the thiol-yne click reaction could be efficiently mediated by
ultrasonic irradiation and implement the ultrasound-assisted thiol-yne click reaction to …

In this work, we demonstrate that highly antibacterially active triazole betaine chitosan (TBC)
component can be incorporated into succinyl chitosan sodium salt (SC-Na) matrix by simple …

The metal-assisted nitrone-nitrile cycloaddition reaction is apply to empower chitosan
chemistry. The ultrasonic irradiation has proven to efficiently accelerate the cycloaddition …