Cognitive dysfunctions, including impaired attention, learning, memory, planning and
problem solving, occur in depressive episodes, often persist during remission, predict …

Objectives: To provide guidance for the management of mood disorders, based on scientific
evidence supplemented by expert clinical consensus and formulate recommendations to …

Major Depressive Disorder (MDD) is a prevalent, chronic, disabling, and multidimensional
mental disorder. Cognitive dysfunction represents a core diagnostic and symptomatic …

Brain diseases are one of the most socially and economically burdening diseases in
Europe. Among all brain diseases, more than 60% of social and economic costs are …

Background Cognitive dysfunction in major depressive disorder (MDD) encompasses
several domains, including but not limited to executive function, verbal memory, and …

Introduction The microbiota-gut-brain axis is a term that is commonly used and covers a
broad set of functions and interactions between the gut microbiome, endocrine, immune and …

Although they are primitive vertebrates, zebrafish (Danio rerio) and medaka (Oryzias latipes)
have surpassed other animals as the most used model organisms based on their many …

Homocysteine (Hcy) is a nonproteogenic sulfur containing amino acid derived from dietary
methionine through demethylation. Homocysteine can be re‐methylated to methionine …

Prefrontal cortical executive functions comprise a number of cognitive capabilities necessary
for goal directed behavior and adaptation to a changing environment. Executive dysfunction …

Impaired cognition is often overlooked in the clinical management of depression, despite its
association with poor psychosocial functioning and reduced clinical engagement. There is …