Warburg effect in colorectal cancer: the emerging roles in tumor microenvironment and therapeutic implications
X Zhong, X He, Y Wang, Z Hu, H Huang, S Zhao… - Journal of hematology & …, 2022 - Springer
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
cancer-related death worldwide. Countless CRC patients undergo disease progression. As …
cancer-related death worldwide. Countless CRC patients undergo disease progression. As …
The Warburg effect 97 years after its discovery
RM Pascale, DF Calvisi, MM Simile, CF Feo, F Feo - Cancers, 2020 - mdpi.com
Simple Summary The deregulation of the oxidative metabolism in cancer cells,
characterized by an increased ratio between glycolysis and oxygen consumption (Warburgv …
characterized by an increased ratio between glycolysis and oxygen consumption (Warburgv …
LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer
Y Wang, JH Lu, QN Wu, Y Jin, DS Wang, YX Chen… - Molecular cancer, 2019 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) play nonnegligible roles in the
epigenetic regulation of cancer cells. This study aimed to identify a specific lncRNA that …
epigenetic regulation of cancer cells. This study aimed to identify a specific lncRNA that …
Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?
N Hay - Nature Reviews Cancer, 2016 - nature.com
In recent years there has been a growing interest among cancer biologists in cancer
metabolism. This Review summarizes past and recent advances in our understanding of the …
metabolism. This Review summarizes past and recent advances in our understanding of the …
Drosophila melanogaster: A Model Organism to Study Cancer
Z Mirzoyan, M Sollazzo, M Allocca, AM Valenza… - Frontiers in …, 2019 - frontiersin.org
Cancer is a multistep disease driven by the activation of specific oncogenic pathways
concomitantly with the loss of function of tumor suppressor genes that act as sentinels to …
concomitantly with the loss of function of tumor suppressor genes that act as sentinels to …
Cancer-associated fibroblasts employ NUFIP1-dependent autophagy to secrete nucleosides and support pancreatic tumor growth
M Yuan, B Tu, H Li, H Pang, N Zhang, M Fan, J Bai… - Nature cancer, 2022 - nature.com
Cancer-associated fibroblasts (CAFs) are one of the most prominent and active components
in the pancreatic tumor microenvironment. Our data show that CAFs are critical for survival …
in the pancreatic tumor microenvironment. Our data show that CAFs are critical for survival …
Disruption of the circadian clock drives Apc loss of heterozygosity to accelerate colorectal cancer
An alarming rise in young onset colorectal cancer (CRC) has been reported; however, the
underlying molecular mechanism remains undefined. Suspected risk factors of young onset …
underlying molecular mechanism remains undefined. Suspected risk factors of young onset …
Glucose metabolism and glucose transporters in breast cancer
E Shin, JS Koo - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Breast cancer is the most common malignancy in women worldwide and is associated with
high mortality rates despite the continuously advancing treatment strategies. Glucose is …
high mortality rates despite the continuously advancing treatment strategies. Glucose is …
LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis
Q Hua, M Jin, B Mi, F Xu, T Li, L Zhao, J Liu… - Journal of hematology & …, 2019 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) have been associated with non-
small cell lung cancer (NSCLC), but the underlying molecular mechanisms of their specific …
small cell lung cancer (NSCLC), but the underlying molecular mechanisms of their specific …
Rewiring urea cycle metabolism in cancer to support anabolism
Cancer cells reprogramme metabolism to maximize the use of nitrogen and carbon for the
anabolic synthesis of macromolecules that are required during tumour proliferation and …
anabolic synthesis of macromolecules that are required during tumour proliferation and …