The adipose tissue organ is organised as distinct anatomical depots located all along the
body axis and it is constituted of three different types of adipocytes: white, beige and brown …

Adipose tissue is a critical regulator of systemic metabolism and bodily homeostasis as it
secretes a myriad of adipokines, including inflammatory and anti-inflammatory cytokines. As …

Obesity occurs when excess energy accumulates in white adipose tissue (WAT), whereas
brown adipose tissue (BAT), which is specialized in dissipating energy through …

The possibility that brown adipose tissue thermogenesis can be recruited in order to combat
the development of obesity has led to a high interest in the identification of “browning …

Thermogenesis by uncoupling protein 1 (UCP1) is one of the primary mechanisms by which
brown adipose tissue (BAT) increases energy expenditure. UCP1 resides in the inner …

The canonical view about the effect of thyroid hormones (THs) on thermogenesis assumes
that the hypothalamus acts merely as a modulator of the sympathetic outflow on brown …

The rise in obesity over the last several decades has reached pandemic proportions. Brown
adipose tissue (BAT) is a thermogenic organ that is involved in energy expenditure and …

Chronic inflammation in adipose tissue may contribute to depot-specific adipose tissue
expansion, leading to obesity and insulin resistance. Dietary supplementation with quercetin …

The conversion of white adipocytes to thermogenic beige adipocytes represents a potential
mechanism to treat obesity and related metabolic disorders. However, the mechanisms …

Elevated serum concentrations of glucocorticoids (GCs) result in excessive lipid
accumulation in white adipose tissue (WAT) as well as dysfunction of thermogenic brown …