Bone remodeling is tightly controlled by osteoclast-mediated bone resorption and osteoblast-
mediated bone formation. Fine tuning of the osteoclast–osteoblast balance results in strict …

In the era of personalized/precision health care, additional effort is being expended to
understand the biology and molecular mechanisms of disease processes. How these …

The senescence-associated secretory phenotype (SASP), which accumulates over the
course of normal aging and in age-related diseases, is a crucial driver of chronic …

Macrophage pyroptosis drives the secretion of IL-1β, which has been recently reported to be
a featured salivary biomarker for discriminating periodontitis in the presence of diabetes …

Active matrix metalloproteinase-8 (aMMP-8) is a promising biomarker candidate for the
modern periodontal and peri-implant disease diagnostics utilizing the chairside/point-of-care …

Among pro-inflammatory cytokines, Interleukin-1β is crucially involved in several
inflammatory-based diseases and even cancer. Increased Interleukin-1β levels in oral fluids …

Aim The systematic review aimed to compare the levels of advanced glycation end products
(AGEs) and RAGE (AGE receptors) expression in diabetic periodontitis patients with non …

Background Metalloproteinases are proteolytic enzymes that degrade dentin and
periodontal collagen; therefore, it is of special interest that dental students know its …

Periodontitis and chronic obstructive pulmonary disease (COPD) are chronic inflammatory
diseases with common risk factors, such as long-term smoking, age, and social deprivation …

Abstract Background and Objective Biological regulators of periodontal inflammation,
collagen degradation, and insulin resistance have not been determined in association with …