Abstract Major Depressive Disorder (MDD) or depression is a pathological mental condition
affecting millions of people worldwide. Identification of objective biological markers of …

Major depressive disorder (MDD) is one of the most serious diseases and now becomes a
major public health problem in the world. The pathogenesis of depression remains poorly …

Background Fibroblast Growth Factor 2 (FGF2) is a neurotrophic protein that has been
implicated as a biomarker for anxiety and depressive disorders, which comprise a significant …

Depression, a prevalent psychiatric malady, afflicts a substantial global demographic,
engendering considerable disease burden due to its elevated morbidity and mortality rates …

Both the brain-derived neurotrophic factor (BDNF) and glucocorticoids (GCs) play multiple
roles in various aspects of neurons, including cell survival and synaptic function. BDNF and …

Stress, a risk factor for major depressive disorder and Alzheimer disease, leads to the
release of high-mobility group box-1 (HMGB1) protein, which in turn causes …

Social anhedonia is a psychological state with difficulty in experiencing pleasure from social
interactions and is observed in various diseases, such as depressive disorders. Although …

The role of the fibroblast growth factor (FGF) system in depression has received
considerable attention in recent years. To understand the role of this system, it is important to …

成纤维细胞生长因子（ FGF） 是一组家族性结构相关的蛋白多肽， 与其受体构成了一个复杂的
信号系统。 近年来， 越来越多证据表明FGF 家族在中枢神经系统损伤修复中起到关键作用 …

Both brain-derived neurotrophic factor (BDNF) and glucocorticoids (GCs) have multiple roles
in the various aspects of neurons, including cell survival and synaptic function. BDNF and its …