The mechanism of microglia-mediated immune inflammation in ischemic stroke and the role of natural botanical components in regulating microglia: A review

J Zeng, T Bao, K Yang, X Zhu, S Wang… - Frontiers in …, 2023 - frontiersin.org
Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …

Tetramethylpyrazine in Chinese baijiu: Presence, analysis, formation, and regulation

X Shi, S Zhao, S Chen, X Han, Q Yang, L Zhang… - Frontiers in …, 2022 - frontiersin.org
Traditional Chinese fermented baijiu is one of the six major distilled spirits consumed
worldwide. It plays an important role in people's daily life and social interactions because of …

SIRT1 activation by 2, 3, 5, 6-tetramethylpyrazine alleviates neuroinflammation via inhibiting M1 microglia polarization

Y Chen, F Peng, C Yang, H Hou, Z Xing… - Frontiers in …, 2023 - frontiersin.org
Background Neuroinflammation has been reported as a potential contributing factor to brain
diseases, and is characterized by activated microglia with release of multiple inflammatory …

Unraveling the aroma profiling of Baijiu: Sensory characteristics of aroma compounds, analytical approaches, key odor-active compounds in different Baijiu, and their …

L Wang, P Tang, P Zhang, J Lu, Y Chen, D Xiao… - Trends in Food Science …, 2024 - Elsevier
Background More than 2700 trace compounds were reported in Chinese Baijiu. Among
these compounds, odor-active compounds (OACs) can directly exhibit sensory …

Understanding mechanistic aspect of the therapeutic role of herbal agents on neuroplasticity in cerebral ischemic-reperfusion injury

A Bangar, H Khan, A Kaur, K Dua, TG Singh - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Stroke is one of the leading causes of death and disability.
The only FDA-approved therapy for treating stroke is tissue plasminogen activator (tPA) …

East meets west in alcoholic beverages: Flavor comparison, microbial metabolism and health effects

M Lin, B Yang, M Dai, Y Xu, X Li, B Sun - Food Bioscience, 2023 - Elsevier
As one kind of beverages, alcoholic beverage is deeply loved by people around the world.
Affected by factors such as raw materials, geographical environment, and brewing …

Research on the mechanism of antidepressive effect of Suanzaoren Decoction through TLR4/MyD88/NF-κB pathway and Wnt/β-catenin pathway

Y Du, T Yan, B Wu, B He, Y Jia - Journal of ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance Increased inflammatory response and disruption of
neuroplasticity are important mechanisms in the hypothesis of the pathogenesis of …

[HTML][HTML] Dissolving microneedle patches-mediated percutaneous delivery of tetramethylpyrazine for rheumatoid arthritis treatment

W Zhao, L Zheng, J Yang, Y Li, Y Zhang, T Ma… - European Journal of …, 2023 - Elsevier
Recently, transdermal treatment of rheumatoid arthritis (RA) has received increasing
attention due to the advantages of improving patient compliance and avoiding …

Mechanism of molecular interaction between pyrazine flavor substances and lysozyme: based on spectroscopy and molecular docking studies

W Tong, Y Li, Z Huang, S Wang, G Chen, X Liu… - Journal of Molecular …, 2023 - Elsevier
Volatile flavor substances in food have received greater attention owing to the love for
flavored foods. In this study, a series of spectroscopic and molecular docking techniques …

Post-stroke cognitive impairment and synaptic plasticity: A review about the mechanisms and Chinese herbal drugs strategies

X Chi, L Wang, H Liu, Y Zhang, W Shen - Frontiers in Neuroscience, 2023 - frontiersin.org
Post-stroke cognitive impairment, is a major complication of stroke, characterized by
cognitive dysfunction, which directly affects the quality of life. Post-stroke cognitive …