Permeability of the blood‐brain barrier for atenolol studied by positron emission tomography

P Agon, P Goethals, D Van Haver… - Journal of pharmacy …, 1991 - Wiley Online Library
The permeability of the blood‐brain barrier for atenolol, a hydrophilic β‐adrenergic blocking
agent, has been assessed in dogs, by studying the distribution of [11C] atenolol in brain …

Central nervous system side-effects with hydrophilic and lipophilic β-blockers

A Westerlund - European journal of clinical pharmacology, 1985 - Springer
Previous investigations have suggested that hydrophilic β-Blockers, which appear at low
concentrations in brain tissue, are less likely to produce CNS-related side-effects than are …

CNS-related side-effects with metoprolol and atenolol

JR Cove-Smith, CA Kirk - European journal of clinical pharmacology, 1985 - Springer
Vivid and bizarre dreams, hallucinations, sleep disturbance and psychosis have all been
described following treatment with β-Blockers. It has been suggested that these central …

Musical hallucinations induced by propranolol

A Fernandez, TR Crowther… - The journal of nervous …, 1998 - journals.lww.com
Since the late 19th century, French psychiatrists have added to our understanding of brain-
induced hallucinations. The syndrome of musical hallucinosis is a rare form of brain-induced …

Central nervous system considerations in the use of β-blockers, angiotensin-converting enzyme inhibitors, and thiazide diuretics in managing essential hypertension

FM Gengo, C Gabos - American Heart Journal, 1988 - Elsevier
The most common mild side effects occurring with use of β-blockers, thiazide diuretics, and
angiotensin-converting enzyme inhibitors for blood pressure control are central nervous …

Effects of propranolol and atenolol on immobilization stress-induced hypertension and down-regulation of central β-adrenoceptors in rats

M Takita, Y Oda, S Kigoshi, I Muramatsu - Pharmacology Biochemistry and …, 1995 - Elsevier
Effects of chronic treatment with propranolol or atenolol on stress-induced changes in blood
pressure, body weight and cerebral β-adrenoceptors in rats were examined and compared …

Interaction between the beta‐adrenoceptor blockers metoprolol and atenolol with amitriptyline and their effects on oxidative liver metabolism.

W Kirch, H Spahn, NR Kitteringham… - British Journal of …, 1984 - Wiley Online Library
Neither the kinetics of the hydrophilic beta‐adrenoceptor blocker atenolol nor those of the
lipophilic metoprolol were influenced by the concurrent administration of amitriptyline …

Polymorphic metabolism of the β-adrenoreceptor blocking drugs and its clinical relevance

RL Smith - European Journal of Clinical Pharmacology, 1985 - Springer
Although β-Blockers are structurally closely related, there are marked differences in the
extent of metabolism, related mainly to relative lipophilicity. Lipophilic β-Blockers are …

Behavioral sequelae of antihypertensive therapy: A review

MF Muldoon, AP Shapiro, SB Manuck… - Behavioral aspects of …, 2014 - taylorfrancis.com
Antihypertensive medications, although promoted and prescribed primarily for their ability to
reduce arterial blood pressure, have a variety of other effects that significantly affect the lives …

Visual reaction times may be improved by certain β-blockers

D Harms - European Journal of Clinical Pharmacology, 1985 - Springer
The effects of the β-blocker atenolol on vigilance, concentration, and psychophysiological
condition were determined by measuring visual reaction time and choice reaction time in …