Polypharmacy is a major challenge in healthcare for older people, and is associated with
increased risks of adverse outcomes, such as delirium, falls, frailty, cognitive impairment and …

The term polypharmacy was originally coined to refer to problems related to multiple drug
consumption and excessive drug use during the treatment of a disease or disorder. In the …

Objectives: Identify the appropriate indications for the various antipsychotic medications.
Summarize the mechanism of action of both first and second-generation antipsychotics …

Background The quality of life of older people is significantly affected by the way in which
long-term care (LTC) is provided. This presents a challenge to governments to find ways to …

Interpreting results from deprescribing interventions to generate actionable evidence is
challenging owing to inconsistent and heterogeneous outcome definitions between studies …

Objective To examine the prevalence of psychotropic medicine dispensing before and after
older people enter residential care. Design Retrospective national cohort study; analysis of …

Psychotropic medications have a high risk of serious adverse events and small effect size for
changed behaviours for people with dementia. Non-pharmacological approaches are …

Abstract In April, 2019, the Alzheimer's Association Dementia Care Provider Roundtable
convened to discuss common challenges faced when implementing person-centered, non …

Objectives: This study investigated the views of people living with dementia and their
families/care partners on (i) what they find helpful or unhelpful regarding behavioral …

Introduction: Mitigating the burden of unnecessary polypharmacy or multiple medication use
in people living with dementia has been recognized as a key priority internationally. One …