Membranous nephropathy (MN) is characterized histomorphologically by the presence of
immune deposits in the subepithelial space of the glomerular filtration barrier; its clinical …

Membranous nephropathy (MN) is a unique glomerular lesion that is the most common
cause of idiopathic nephrotic syndrome in nondiabetic white adults. About 80% of cases are …

Membranous nephropathy is a major cause of nephrotic syndrome of non-diabetic origin in
adults. It is the second or third leading cause of end-stage renal disease in patients with …

Most glomerulonephritides, even the more common types, are rare diseases. They are
nevertheless important since they frequently affect young people, often cannot be cured, and …

Idiopathic membranous nephropathy (INM) remains a common cause of the nephrotic
syndrome in adults. The autoimmune nature of IMN was clearly delineated in 2009 with the …

Acute kidney injury (AKI) and chronic kidney disease (CKD) are worldwide public health
problems affecting millions of people and have rapidly increased in prevalence in recent …

The phospholipase A2 receptor (PLA2R1) is the major autoantigen in idiopathic
membranous nephropathy. However, the value of anti-PLA2R1 antibody titers in predicting …

The discovery in 2009 of the M-type phospholipase A2 receptor (PLA2R) as the primary
target in membranous nephropathy (MN) greatly advanced basic and clinical research …

Lessons from an animal model that faithfully resembles human membranous nephropathy
(MN) have informed our understanding of the pathogenesis of this organ-specific …

Antibodies of IgG4 subclass are exceptional players of the immune system, as they are
considered to be immunologically inert and functionally monovalent, and as such may be …