Neurobiology of addiction: An integrative review
A Goodman - Biochemical pharmacology, 2008 - Elsevier
Evidence that psychoactive substance use disorders, bulimia nervosa, pathological
gambling, and sexual addiction share an underlying biopsychological process is …
gambling, and sexual addiction share an underlying biopsychological process is …
Current perspectives on selective dopamine D3 receptor antagonists as pharmacotherapeutics for addictions and related disorders
CA Heidbreder, AH Newman - … of the New York Academy of …, 2010 - Wiley Online Library
Repeated exposure to drugs of abuse produces long‐term molecular and neurochemical
changes that may explain the core features of addiction, such as the compulsive seeking …
changes that may explain the core features of addiction, such as the compulsive seeking …
New drugs, old targets: tweaking the dopamine system to treat psychostimulant use disorders
The abuse of illicit psychostimulants such as cocaine and methamphetamine continues to
pose significant health and societal challenges. Despite considerable efforts to develop …
pose significant health and societal challenges. Despite considerable efforts to develop …
The dopamine D3 receptor plays an essential role in alcohol‐seeking and relapse
V Vengeliene, F Leonardi‐Essmann… - The FASEB …, 2006 - Wiley Online Library
Our study aimed to identify new candidate genes, which might be involved in alcohol craving
and relapse. To find changes in gene expression after long‐term alcohol consumption, we …
and relapse. To find changes in gene expression after long‐term alcohol consumption, we …
The neuropharmacology of relapse to food seeking: methodology, main findings, and comparison with relapse to drug seeking
SG Nair, T Adams-Deutsch, DH Epstein… - Progress in …, 2009 - Elsevier
Relapse to old, unhealthy eating habits is a major problem in human dietary treatments. The
mechanisms underlying this relapse are unknown. Surprisingly, until recently this clinical …
mechanisms underlying this relapse are unknown. Surprisingly, until recently this clinical …
Pavlovian-to-instrumental transfer in cocaine seeking rats.
KH LeBlanc, SB Ostlund, NT Maidment - Behavioral neuroscience, 2012 - psycnet.apa.org
Drug-associated cues are believed to be important mediators of addiction and drug relapse.
Although such cues may influence drug-seeking behavior through multiple routes, it is their …
Although such cues may influence drug-seeking behavior through multiple routes, it is their …
The importance of the adenosine A2A receptor-dopamine D2 receptor interaction in drug addiction
M Filip, M Zaniewska, M Frankowska… - Current medicinal …, 2012 - ingentaconnect.com
Drug addiction is a serious brain disorder with somatic, psychological, psychiatric, socio-
economic and legal implications in the developed world. Illegal (eg, psychostimulants …
economic and legal implications in the developed world. Illegal (eg, psychostimulants …
YQA14: a novel dopamine D3 receptor antagonist that inhibits cocaine self‐administration in rats and mice, but not in D3 receptor‐knockout mice
R Song, RF Yang, N Wu, RB Su, J Li, XQ Peng… - Addiction …, 2012 - Wiley Online Library
The dopamine (DA) D3 receptor is posited to be importantly involved in drug reward and
addiction, and D3 receptor antagonists have shown extraordinary promise as potential anti …
addiction, and D3 receptor antagonists have shown extraordinary promise as potential anti …
Aripiprazole for the treatment of methamphetamine dependence: a randomized, double‐blind, placebo‐controlled trial
Aims To test aripiprazole for efficacy in decreasing use in methamphetamine‐dependent
adults, compared to placebo. Design Participants were randomized to receive 12 weeks of …
adults, compared to placebo. Design Participants were randomized to receive 12 weeks of …
Forced abstinence model of relapse to study pharmacological treatments of substance use disorder
CM Reichel, RA Bevins - Current drug abuse reviews, 2009 - ingentaconnect.com
Understanding and preventing relapse to drug use is one of the most difficult challenges
faced by clinicians and practitioners in the struggle to help people remain abstinent. In this …
faced by clinicians and practitioners in the struggle to help people remain abstinent. In this …