Guidelines for reporting outcomes in trial reports: the CONSORT-outcomes 2022 extension
Importance Clinicians, patients, and policy makers rely on published results from clinical
trials to help make evidence-informed decisions. To critically evaluate and use trial results …
trials to help make evidence-informed decisions. To critically evaluate and use trial results …
[HTML][HTML] Diagnostic accuracy of deep learning in medical imaging: a systematic review and meta-analysis
Deep learning (DL) has the potential to transform medical diagnostics. However, the
diagnostic accuracy of DL is uncertain. Our aim was to evaluate the diagnostic accuracy of …
diagnostic accuracy of DL is uncertain. Our aim was to evaluate the diagnostic accuracy of …
[HTML][HTML] An overview of and recommendations for more accessible digital mental health services
Mental health concerns are common, and various evidence-based interventions for mental
health conditions have been developed. However, many people have difficulty accessing …
health conditions have been developed. However, many people have difficulty accessing …
[HTML][HTML] MRI-targeted or standard biopsy in prostate cancer screening
M Eklund, F Jäderling, A Discacciati… - New England journal …, 2021 - Mass Medical Soc
Background High rates of overdiagnosis are a critical barrier to organized prostate cancer
screening. Magnetic resonance imaging (MRI) with targeted biopsy has shown the potential …
screening. Magnetic resonance imaging (MRI) with targeted biopsy has shown the potential …
[HTML][HTML] System usability scale benchmarking for digital health apps: meta-analysis
Background: The System Usability Scale (SUS) is a widely used scale that has been used to
quantify the usability of many software and hardware products. However, the SUS was not …
quantify the usability of many software and hardware products. However, the SUS was not …
Updating guidance for reporting systematic reviews: development of the PRISMA 2020 statement
Objectives To describe the processes used to update the PRISMA 2009 statement for
reporting systematic reviews, present results of a survey conducted to inform the update …
reporting systematic reviews, present results of a survey conducted to inform the update …
Effect of early treatment with ivermectin among patients with Covid-19
G Reis, EASM Silva, DCM Silva… - … England Journal of …, 2022 - Mass Medical Soc
Background The efficacy of ivermectin in preventing hospitalization or extended observation
in an emergency setting among outpatients with acutely symptomatic coronavirus disease …
in an emergency setting among outpatients with acutely symptomatic coronavirus disease …
Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for …
Objective The vitamin D endocrine system may have a variety of actions on cells and tissues
involved in COVID-19 progression especially by decreasing the Acute Respiratory Distress …
involved in COVID-19 progression especially by decreasing the Acute Respiratory Distress …
Ivermectin for preventing and treating COVID‐19
M Popp, M Stegemann, MI Metzendorf… - Cochrane Database …, 2021 - cochranelibrary.com
Background Ivermectin, an antiparasitic agent used to treat parasitic infestations, inhibits the
replication of viruses in vitro. The molecular hypothesis of ivermectin's antiviral mode of …
replication of viruses in vitro. The molecular hypothesis of ivermectin's antiviral mode of …
Guidelines for reporting trial protocols and completed trials modified due to the COVID-19 pandemic and other extenuating circumstances: the CONSERVE 2021 …
Importance Extenuating circumstances can trigger unplanned changes to randomized trials
and introduce methodological, ethical, feasibility, and analytical challenges that can …
and introduce methodological, ethical, feasibility, and analytical challenges that can …