Cancer cachexia: molecular mechanisms and treatment strategies

T Setiawan, IN Sari, YT Wijaya, NM Julianto… - Journal of Hematology & …, 2023 - Springer
Muscle wasting is a consequence of physiological changes or a pathology characterized by
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …

Cancer cachexia: Diagnosis, assessment, and treatment

M Sadeghi, M Keshavarz-Fathi, V Baracos… - Critical reviews in …, 2018 - Elsevier
Cancer cachexia is a multi-factorial syndrome, which negatively affects quality of life,
responsiveness to chemotherapy, and survival in advanced cancer patients. Our …

A narrative review of cancer-related fatigue (CRF) and its possible pathogenesis

S Yang, S Chu, Y Gao, Q Ai, Y Liu, X Li, N Chen - Cells, 2019 - mdpi.com
Many cancer patients suffer from severe fatigue when treated with chemotherapy or
radiotherapy; however, the etiology and pathogenesis of this kind of fatigue remains …

Mechanisms of cancer cachexia

MJ Tisdale - Physiological reviews, 2009 - journals.physiology.org
Up to 50% of cancer patients suffer from a progressive atrophy of adipose tissue and
skeletal muscle, called cachexia, resulting in weight loss, a reduced quality of life, and a …

Sex differences in muscle wasting

LJ Anderson, H Liu, JM Garcia - Sex and gender factors affecting …, 2017 - Springer
With aging and other muscle wasting diseases, men and women undergo similar
pathological changes in skeletal muscle: increased inflammation, enhanced oxidative …

Megestrol acetate for treatment of anorexia‐cachexia syndrome

VR Garcia, E López‐Briz, RC Sanchis… - Cochrane Database …, 2013 - cochranelibrary.com
Background This is an updated version of a previously published review in The Cochrane
Library (2005, Issue 2) on'Megestrol acetate for the treatment of anorexia‐cachexia …

Pathophysiology of anorexia in the cancer cachexia syndrome

CC Ezeoke, JE Morley - Journal of cachexia, sarcopenia and …, 2015 - Wiley Online Library
Anorexia is commonly present in persons with cancer and a major component of cancer
cachexia. There are multiple causes of anorexia in cancer. Peripherally, these can be due to …

Cancer cachexia: developing multimodal therapy for a multidimensional problem

KCH Fearon - European journal of cancer, 2008 - Elsevier
Cancer cachexia is a multi-factorial syndrome that encompasses a spectrum from early
weight loss (pre-cachexia) to a state of severe incapacity incompatible with life. The …

Structure and physiological actions of ghrelin

C Delporte - Scientifica, 2013 - Wiley Online Library
Ghrelin is a gastric peptide hormone, discovered as being the endogenous ligand of growth
hormone secretagogue receptor. Ghrelin is a 28 amino acid peptide presenting a unique n …

[HTML][HTML] Obesity and colorectal cancer: role of adipokines in tumor initiation and progression

S Riondino, M Roselli, R Palmirotta… - World journal of …, 2014 - ncbi.nlm.nih.gov
Obesity-associated diseases account for a large portion of public health challenges. Among
obesity-related disorders, a direct and independent relationship has been ascertained for …