The distribution, molecular structure and role of adenosine A2 receptors in the nervous
system, is reviewed. The adenosine A2a receptor subtype, identified in the nervous system …

The numerous and widespread effecfs of adenosine provide both WI opportunity for the
development of novel therapeutic agents acting via adenosine receptors and the challenge …

Adenosine A 2a receptors are not confined to dopamine-rich areas of the brain, since
thermocycling analysis shows that adenosine A 2a receptor mRNA is expressed also in the …

Endogenous adenosine in nervous tissue, a central link between energy metabolism and
neuronal activity, varies according to behavioral state and (patho) physiological conditions; it …

Endogenous adenosine is a widely distributed upstream regulator of a broad spectrum of
neurotransmitters, receptors, and signaling pathways that converge to contribute to the …

A novel receptor cDNA was isolated from a human hippocampal cDNA library. The encoded
polypeptide contains structural features consistent with its classification as a G protein …

Adenosine is an endogenous nucleoside that modulates many physiological processes. Its
actions are mediated by interaction with specific cell membrane receptors. Four subtypes of …

Publisher Summary Adenosine exerts physiological effects on the nervous system through
interactions with cell surface receptors. In the nervous system adenosine has been shown to …

Recent studies have shown the existence of a specific antagonistic interaction between
adenosine A 2a receptors and dopamine D 2 receptors in the brain. This A 2a-D 2 …

Several lines of evidence indicate that interactions among transmission lines can take place
at the level of the cell membrane via interactions among macromolecules, integral or …