A1 adenosine receptor agonists: medicinal chemistry and therapeutic potential
SA Hutchinson, PJ Scammells - Current pharmaceutical design, 2004 - ingentaconnect.com
Adenosine receptors are widely distributed in the body and modulate numerous
physiological processes. Four receptor subtypes (termed A1, A2A, A2B and A3) have been …
physiological processes. Four receptor subtypes (termed A1, A2A, A2B and A3) have been …
Adenosine receptor‐mediated modulation of acetylcholine release from rat striatal synaptosomes
KA Kirkpatrick, PJ Richardson - British journal of pharmacology, 1993 - Wiley Online Library
1 The effects of A1 and A2a adenosine receptor agonists on the veratridine‐evoked release
of [3H]‐acetylcholine ([3H]‐ACh) from rat striatal synaptosomes was investigated by use of …
of [3H]‐acetylcholine ([3H]‐ACh) from rat striatal synaptosomes was investigated by use of …
[PDF][PDF] Functional expression of adenosine A2b receptor in Xenopus oocytes.
JL Yakel, RA Warren, SM Reppert, RA North - Molecular pharmacology, 1993 - Citeseer
SUMMARY RNA was transcribed in vitro from a cDNA clone (RFL9) that encodes the rat
adenosine A2b receptor. Xenopus oocytes that had been injected with this RNA several …
adenosine A2b receptor. Xenopus oocytes that had been injected with this RNA several …
Characterization of the human brain putative A2B adenosine receptor expressed in Chinese hamster ovary (CHO.A2B4) cells
SPH Alexander, J Cooper, J Shine… - British journal of …, 1996 - Wiley Online Library
1 An [3H]‐adenine pre‐labelling methodology was employed to assay cyclic AMP
generation by adenosine analogues in Chinese hamster ovary (CHO. A2B4) cells …
generation by adenosine analogues in Chinese hamster ovary (CHO. A2B4) cells …
Purinoceptor modulation of noradrenaline release in rat tail artery: tonic modulation mediated by inhibitory P2Y‐ and facilitatory A2A‐purinoceptors
J Gonçalves, G Queiroz - British journal of pharmacology, 1996 - Wiley Online Library
1 The effects of analogues of adenosine and ATP on noradrenaline release elicited by
electrical stimulation (5 Hz, 2700 pulses) were studied in superfused preparations of rat tail …
electrical stimulation (5 Hz, 2700 pulses) were studied in superfused preparations of rat tail …
Reduction in cerebral ischemic injury in the newborn rat by potentiation of endogenous adenosine
JM Gidday, JC Fitzgibbons, AR Shah, MJ Kraujalis… - Pediatric …, 1995 - nature.com
Because of ontogenic influences on the pathophysiologic mechanisms of brain injury in the
perinatal brain, and in particular, the incomplete development of adenosine receptor …
perinatal brain, and in particular, the incomplete development of adenosine receptor …
[PDF][PDF] Characterization of adenosine receptors in human erythroleukemia cells and platelets: further evidence for heterogeneity of adenosine A2 receptor subtypes.
I Feoktistov, I Biaggioni - Molecular pharmacology, 1993 - Citeseer
Adenosine receptors are present in platelets, and their activation results in accumulation of
cAMP and inhibition of aggregation. The study of platelet adenosine receptors, however, is …
cAMP and inhibition of aggregation. The study of platelet adenosine receptors, however, is …
Enabling role of adenosine A1 receptors in adenosine A2A receptor‐mediated striatal expression of c‐fos
M Karcz‐Kubicha, D Quarta, BT Hope… - European Journal of …, 2003 - Wiley Online Library
When striatal neurons are strongly activated they produce adenosine, which activates
nearby adenosine A1 receptors (A1Rs) and adenosine A2A receptors (A2ARs). Although …
nearby adenosine A1 receptors (A1Rs) and adenosine A2A receptors (A2ARs). Although …
Modulation by adenosine of Aδ and C primary-afferent glutamatergic transmission in adult rat substantia gelatinosa neurons
LJ Lao, Y Kawasaki, K Yang, T Fujita, E Kumamoto - Neuroscience, 2004 - Elsevier
The present study examined the actions of adenosine on monosynaptic Aδ and C primary-
afferent excitatory postsynaptic currents (EPSCs) recorded from substantia gelatinosa (SG) …
afferent excitatory postsynaptic currents (EPSCs) recorded from substantia gelatinosa (SG) …
The Adenosine Receptors Present on the Plasma Membrane of Chromaffin Cells Are of the A2b Subtype
The adenosine receptors in the plasma membrane of chromaffin cells from bovine adrenal
medulla were characterized. The presence of A1 receptors was discounted owing to the …
medulla were characterized. The presence of A1 receptors was discounted owing to the …