Serotonin has been implicated in the control of satiety for almost four decades. Historically,
the insight that the appetite suppressant effect of fenfluramine is linked to serotonin has …

About half of all cancer patients show a syndrome of cachexia, characterized by anorexia
and loss of adipose tissue and skeletal muscle mass. Cachexia can have a profound impact …

Background & Aims: Ghrelin, an endogenous ligand for growth hormone secretagogue
receptor, was recently identified in the rat stomach. We examined the effects of the gastric …

Cachexia is among the most debilitating and life‐threatening aspects of cancer. Associated
with anorexia, fat and muscle tissue wasting, psychological distress, and a lower quality of …

Ghrelin, an endogenous ligand for growth hormone secretagogue (GHS) receptor originally
isolated from the stomach, occurs in the hypothalamic arcuate nucleus and may play a role …

Obesity represents the most prevalent nutritional problem worldwide which in the long run
predisposes to development of diabetes mellitus, hypertension, endometrial carcinoma …

Recent progress in the field of energy homeostasis was triggered by the discovery of
adipocyte hormone leptin and revealed a complex regulatory neuroendocrine network. A …

Background/Aims: The gastric peptide ghrelin, an endogenous ligand for growth-hormone
secretagogue receptor, has two major molecular forms: acylated ghrelin and desacyl …

Background and aims: Ghrelin, an endogenous ligand for growth hormone secretagogue
receptor (GHS-R), is an appetite stimulatory signal from the stomach with structural …

Animals display stereotyped behavioral modifications during development, but little is known
about how genes and neural circuits are regulated to turn on/off behaviors. Here we report …