ACCF/AHA 2011 expert consensus document on hypertension in the elderly: a report of the American College of Cardiology Foundation Task Force on Clinical Expert …

WS Aronow, JL Fleg, CJ Pepine, NT Artinian, G Bakris… - Circulation, 2011 - Am Heart Assoc
This document was written with the intent to be a complete reference at the time of
publication on the topic of managing hypertension in the elderly. Given the length of the …

Three generations of β-blockers: history, class differences and clinical applicability

GT do Vale, CS Ceron, NA Gonzaga… - Current hypertension …, 2019 - ingentaconnect.com
Background: Beta-adrenergic receptors are expressed in cardiomyocytes and activated by
either noradrenaline released from sympathetic synapses or circulating catecholamines …

A review of nebivolol pharmacology and clinical evidence

J Fongemie, E Felix-Getzik - Drugs, 2015 - Springer
Nebivolol is a highly selective β 1-adrenergic receptor antagonist with a pharmacologic
profile that differs from those of other drugs in its class. In addition to cardioselectivity …

Beta-blockers in hypertension

CVS Ram - The American journal of cardiology, 2010 - Elsevier
Beta blockers have been used in the treatment of cardiovascular conditions for decades.
Despite a long history and status as a guideline-recommended treatment option for …

Nebivolol: A Highly Selective β1‐Adrenergic Receptor Blocker That Causes Vasodilation by Increasing Nitric Oxide

S Gupta, HM Wright - Cardiovascular therapeutics, 2008 - Wiley Online Library
Nebivolol (Bystolic®) is a cardioselective beta 1 (β1)‐adrenergic receptor blocker with
endothelium‐dependent vasodilating properties. The endothelium‐dependent relaxation …

Nebivolol: Haemodynamic effects and clinical significance of combined β-blockade and nitric oxide release

O Kamp, M Metra, S Bugatti, L Bettari, A Dei Cas… - Drugs, 2010 - Springer
Nebivolol is a third-generation β-adrenergic receptor antagonist (β-blocker) with high
selectivity for β 1-adrenergic receptors. In addition, it causes vasodilatation via interaction …

Blood pressure lowering efficacy of beta‐1 selective beta blockers for primary hypertension

GWK Wong, HN Boyda… - Cochrane Database of …, 2016 - cochranelibrary.com
Background Beta blockers are commonly used to treat hypertension. The blood pressure
reading is the primary tool for physicians and patients to assess the efficacy of the treatment …

[HTML][HTML] Nebivolol (bystolic), a novel beta blocker for hypertension

O Hilas, D Ezzo - Pharmacy and Therapeutics, 2009 - ncbi.nlm.nih.gov
Hypertension is an asymptomatic condition of persistently elevated blood pressure (BP) that
affects approximately 50 million Americans and one billion people worldwide. 1, 2 It has …

Effect of beta-1-blocker, nebivolol, on central aortic pressure and arterial stiffness in patients with essential hypertension

R Soanker, MUR Naidu, SB Raju… - Indian journal of …, 2012 - journals.lww.com
Materials and Methods: In this single arm, open-labeled study, 13 patients were given
nebivolol, 5 mg orally once daily for 15 days. Primary outcome was change in central aortic …

Effect of placebo groups on blood pressure in hypertension: a meta-analysis of beta-blocker trials

M Wilhelm, A Winkler, W Rief, BK Doering - Journal of the American Society …, 2016 - Elsevier
Hypertension is often treated pharmacologically. Since there is evidence that the
cardiovascular system is sensitive to placebo mechanisms, our aim was to conduct an effect …