miRNAs are some of the most well-characterized regulators of gene expression. Integral to
several physiological processes, their aberrant expression often drives the pathogenesis of …

Background MicroRNA-155 has been discussed as a biomarker in cancer diagnosis and
prognosis. Although relevant studies have been published, the role of microRNA-155 …

Highlights•Liquid biopsy-based early disease detection assays are key enablers of
preventive healthcare.•Circulatory miRNAs are promising liquid biopsy biomarkers that are …

Breast cancer (BC) remains the most prevalent malignancy due to its incidence rate,
recurrence, and metastasis in women. Conventional strategies of cancer detection …

Background Cervical cancer is a preventable disease, but it is a major public health problem
despite having a good prognosis when diagnosed early. Although the Pap smear has led to …

Premature ovarian insufficiency (POI) is a typical disorder of amenorrhea that lasts for a
minimum of four months in women< 40 years old and is typically characterized by reduced …

Background Colorectal cancer is one of the most common malignancy in the world. It has
been reported that cancer stem cells (CSCs) serve as the primary drivers of tumorigenesis …

Background Phthalates are commonly used in variety of plastic products. Previously it has
been revealed that di (2-ethylhexyl) phthalate (DEHP), as the most common member of the …

MicroRNAs are a class of small non-coding RNA molecules that regulate gene expression
on post-transcriptional level. Their biogenesis consists of a complex series of sequential …

Cancer is a complex and heterogeneous disease that poses a significant threat to global
health. Early diagnosis and treatment are critical for improving patient outcomes, and the …