In order to study whether the methacholine inhalation challenge could predict which patients
with allergic rhinitis were at risk to develop asthma, we prospectively studied a group of …

Three patients with recurrent emergency room visits and hospitalizations for bronchial
asthma are described. Although each patient had respiratory distress associated with …

Cough is a complex physiologic event that protects the lungs from mechanical, chemical,
and thermal injury. It is a normal reflex and therefore helps humans to adapt to an …

Wheezing results from flow limitation in intra-thoracic airways. It may be caused by a variety
of mechanisms, including inflammation, edema, secretions, and tumors of the airways as …

Background It is now recognized that asthma can present in different forms. Typically,
asthma present with symptoms of wheeze, breathlessness and cough. Atypical forms of …

Cough is a common symptom in the smoking and non-smoking patient seeking medical
attention from the office-based physician. Often, a comprehensive history and physical …

Background Asthmatic patients with chest tightness as their only presenting symptom (chest
tightness variant asthma [CTVA]) have clinical characteristics of eosinophilic airway …

BACKGROUND: Asthma can manifest in a variety of clinical phenotypes like cough variant
asthma, chest tightness variant asthma (CTVA), and masked asthma. Patients with CTVA …

Methacholine sensitivity was evaluated in 166 young subjects who had normal resting
spirometric values but who presented problems suggesting lower airways hyperreactivity …

Melvin R. Pratter, MD, FCCP; t and RichardS. Irwin, MD, FCCP~ though a great deal has
been written about the value of bronchoprovocation challenge, it has been its research …