[HTML][HTML] Human papillomavirus genomics: Understanding carcinogenicity

CW Nelson, L Mirabello - Tumour Virus Research, 2023 - Elsevier
Human papillomavirus (HPV) causes virtually all cervical cancers and many cancers at other
anatomical sites in both men and women. However, only 12 of 448 known HPV types are …

Molecular biology of human papillomavirus infection and cervical cancer

J Doorbar - Clinical science, 2006 - portlandpress.com
HPVs (human papillomaviruses) infect epithelial cells and cause a variety of lesions ranging
from common warts/verrucas to cervical neoplasia and cancer. Over 100 different HPV types …

[HTML][HTML] Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus

J Zhao, EE Lee, J Kim, R Yang, B Chamseddin… - Nature …, 2019 - nature.com
Single-stranded circular RNAs (circRNAs), generated through 'backsplicing', occur more
extensively than initially anticipated. The possible functions of the vast majority of circRNAs …

The papillomavirus life cycle

J Doorbar - Journal of clinical virology, 2005 - Elsevier
Papillomaviruses infect epithelial cells, and depend on epithelial differentiation for
completion of their life cycle. The expression of viral gene products is closely regulated as …

Pathogenesis of human papillomaviruses in differentiating epithelia

MS Longworth, LA Laimins - Microbiology and molecular biology …, 2004 - Am Soc Microbiol
Human papillomaviruses (HPV) are the etiological agents of cervical and other anogenital
malignancies. Over 100 different types of HPVs have been identified to date, and all target …

Persistence of human papillomavirus infection: keys to malignant progression

J Bodily, LA Laimins - Trends in microbiology, 2011 - cell.com
Human papillomaviruses (HPVs) are the etiologic agents of cervical and other epithelial
cancers. Persistence of infections by high-risk HPV types is the single greatest risk factor for …

[HTML][HTML] Prevention of cervical cancer through papillomavirus vaccination

IH Frazer - Nature Reviews Immunology, 2004 - nature.com
A subset of human papillomaviruses (HPVs) promote anogenital malignancy, including
cervical cancer, and prevention and treatment strategies that reflect the causal role of HPV …

Human papillomavirus 42 drives digital papillary adenocarcinoma and elicits a germ cell–like program conserved in HPV-positive cancers

L Leiendecker, T Neumann, PS Jung, SM Cronin… - Cancer Discovery, 2023 - AACR
The skin is exposed to viral pathogens, but whether they contribute to the oncogenesis of
skin cancers has not been systematically explored. Here we investigated 19 skin tumor …

Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31

YE Chang, LA Laimins - Journal of virology, 2000 - Am Soc Microbiol
Human papillomaviruses (HPVs) infect keratinocytes and induce proliferative lesions. In
infected cells, viral gene products alter the activities of cellular proteins, such as Rb and p53 …

[HTML][HTML] Productive lifecycle of human papillomaviruses that depends upon squamous epithelial differentiation

N Kajitani, A Satsuka, A Kawate, H Sakai - Frontiers in microbiology, 2012 - frontiersin.org
Human papillomaviruses (HPVs) target the stratified epidermis, and can causes diseases
ranging from benign condylomas to malignant tumors. Infections of HPVs in the genital tract …