There is a growing body of evidence suggesting that alterations in the adhesion properties
of neoplastic cells endow them with an invasive and migratory phenotype. Indeed, changes …

Advances in our understanding of the mechanisms of lamellipodia and filopodia assembly
have led to a better concept of how cells move, including how the actin cytoskeleton might …

BACKGROUND Prostate tumors shed circulating tumor cells (CTCs) into the blood stream.
Increased evidence shows that CTCs are often present in metastatic prostate cancer and …

Metastasis accounts for the vast majority of morbidity and mortality associated with
melanoma. Evidence suggests melanoma has a predilection for metastasis to particular …

Colorectal cancer (CRC) is one of the most commonly diagnosed and lethal cancers
worldwide. It is a multistep process that requires the accumulation of genetic/epigenetic …

Cancer is a leading cause of death worldwide, and its incidence is rising with numbers
expected to increase 70% in the next two decades. The fact that current mainline treatments …

Antibody targeting of cancer is showing clinical and commercial success after much intense
research and development over the last 30 years. They still have the potential to delivery …

Apigenin (4′, 5, 7‐trihydroxyflavone, 5, 7‐dihydroxy‐2‐(4‐hydroxyphenyl)‐4H‐1‐
benzopyran‐4‐one) is a flavonoid found in many fruits, vegetables, and herbs, the most …

Abstract Galectin-3, a unique chimera-type member of the β-galactoside-binding soluble
lectin family, is widely expressed in numerous cells. Here, we discuss the role of Galectin-3 …

Angiogenesis is a requirement for tumor growth and metastasis. The angiogenic process
depends on vascular endothelial cell migration and invasion, and is regulated by various …