[HTML][HTML] Superoxide dismutase@ zeolite imidazolate framework-8 attenuates noise-induced hearing loss in rats

Y Zhang, Q Li, C Han, F Geng, S Zhang, Y Qu… - Frontiers in …, 2022 - frontiersin.org
Reactive oxygen species (ROS) and inflammation have been considered major contributors
to noise-induced hearing loss (NIHL) that constituted a public health threat worldwide …

[HTML][HTML] Intratympanic steroid injection

C de Cates, R Winters - 2021 - europepmc.org
Objectives: Outline the steps of intratympanic steroid injection. Describe the indications for
an intratympanic steroid injection. Explain the physiology of intratympanic steroid injection …

Otic drug delivery systems: formulation principles and recent developments

X Liu, M Li, H Smyth, F Zhang - Drug Development and Industrial …, 2018 - Taylor & Francis
Disorders of the ear severely impact the quality of life of millions of people, but the treatment
of these disorders is an ongoing, but often overlooked challenge particularly in terms of …

Silicone matrices for controlled dexamethasone release: toward a better understanding of the underlying mass transport mechanisms

T Rongthong, A Qnouch, M Maue Gehrke… - Regenerative …, 2023 - academic.oup.com
Dexamethasone-loaded silicone matrices offer an interesting potential as innovative drug
delivery systems, eg for the treatment of inner ear diseases or for pacemakers. Generally …

Personalized Porous Gelatin Methacryloyl Sustained‐Release Nicotinamide Protects Against Noise‐Induced Hearing Loss

B Feng, T Dong, X Song, X Zheng, C Jin… - Advanced …, 2024 - Wiley Online Library
There are no Food and Drug Administration‐approved drugs for treating noise‐induced
hearing loss (NIHL), reflecting the absence of clear specific therapeutic targets and effective …

[HTML][HTML] Drug diffusion along an intact mammalian cochlea

II Sadreev, GWS Burwood, SM Flaherty… - Frontiers in Cellular …, 2019 - frontiersin.org
Intratympanic drug administration depends on the ability of drugs to pass through the round
window membrane (RW) at the base of the cochlea and diffuse from this location to the …

Пористый кремний как наноматериал для дисперсных транспортных систем направленной лекарственной доставки ко внутреннему уху

ЮМ Спивак, АО Белорус, АА Паневин… - Журнал технической …, 2018 - mathnet.ru
Методом электрохимического анодного травления монокристаллического кремния в
электролите на основе раствора HF с последующим изменением режимов …

Ototoxicity: a high risk to auditory function that needs to be monitored in drug development

MP Pasdelou, L Byelyayeva, S Malmström… - Frontiers in Molecular …, 2024 - frontiersin.org
Hearing loss constitutes a major global health concern impacting approximately 1.5 billion
people worldwide. Its incidence is undergoing a substantial surge with some projecting that …

[HTML][HTML] Functionalisation of silicone by drug-embedded chitosan nanoparticles for potential applications in otorhinolaryngology

U Ajdnik, LF Zemljič, M Bračič, U Maver, O Plohl… - Materials, 2019 - mdpi.com
Silicones are widely used medical materials that are also applied for tympanostomy tubes
with a trending goal to functionalise the surface of the latter to enhance the healing of ear …

Small‐Scale Biological and Artificial Multidimensional Sensors for 3D Sensing

K Agarwal, S Hwang, A Bartnik, N Buchele, A Mishra… - Small, 2018 - Wiley Online Library
A vast majority of existing sub‐millimeter‐scale sensors have a planar, 2D geometry as a
result of conventional top‐down lithographic procedures. However, 2D sensors often suffer …