Lipids are essential constituents of cellular membranes. Once regarded merely as structural
components, lipids have taken centre stage with the discovery of their roles in cell signalling …

In the almost 70 years since the first hints of its existence, the phosphoinositide,
phosphatidyl-D-myo-inositol 4, 5-bisphosphate has been found to be central in the …

During the late phase of HIV type 1 (HIV-1) infection cycle, the virally encoded Gag
polyproteins are targeted to the inner leaflet of the plasma membrane (PM) for assembly …

Many signal transductions resulting from ligand–receptor interactions occur at the cell
surface. These signaling pathways play essential roles in cell polarization, membrane …

By study of asymmetric membranes, models of the cell plasma membrane (PM) have
improved, with more realistic properties of the asymmetric lipid composition of the …

The Arf family proteins are best known for their roles in the vesicle biogenesis. However,
they also play fundamental roles in a wide range of cellular regulation besides vesicular …

Abstract Neurofibromatosis type 2 (NF2), which encodes merlin (moesin-ezrin-radixin-like
protein), belongs to the band 4.1, ezrin, radixin, moesin (FERM) domain-containing 4.1 …

Formation of Ras multimers, including dimers and nanoclusters, has emerged as an
exciting, new front of research in the 'old'field of Ras biomedicine. With significant advances …

Phosphoinositides are a biologically essential class of phospholipids that contribute to
organelle membrane identity, modulate membrane trafficking pathways, and are central …

Phosphoinositides, a small group of lipids found in all cellular membranes, have recently
garnered heightened attention due to their crucial roles in diverse biological processes and …