Accumulating evidence suggests that distinct aspects of successful navigation—path
integration, spatial-knowledge acquisition, and navigation strategies—change with …

Age-related spatial navigation decline is more pronounced in patients with mild cognitive
impairment (MCI) and Alzheimer's disease (AD) dementia. We used a realistic-looking …

GPS navigation is commonplace in everyday life. While it has the capacity to make our lives
easier, it is often used to automate functions that were once exclusively performed by our …

Poor sleep quality is associated with age-related cognitive decline, and whether reversal of
these alterations is possible is unknown. In this study, we report how sleep deprivation (SD) …

Being able to navigate, recall important locations, and find the way home are critical skills,
essential for survival for both humans and animals. These skills can be examined in the …

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Age-related decline in spatial navigation is well-known and the extant literature emphasizes
the important contributions of a hippocampus-dependent spatial navigation system in …

The current “one size fits all” approach to our cognitive aging population is not adequate to
close the gap between cognitive health span and lifespan. In this review article, we present …

Path integration plays a vital role in navigation: it enables the continuous tracking of one's
position in space by integrating self-motion cues. Path integration abilities vary widely …

Decline in cognitive performance, an aspect of the normal aging process, is influenced by
the endocannabinoid system (ECS). Cannabinoid receptor 1 (CB1) signaling diminishes …