Human cytomegalovirus (HCMV) is a herpesvirus that infects between 40% and 95% of the
population worldwide, usually without symptoms. The host immune response keeps the …

Over 50 years of cancer research has resulted in the generation of massive amounts of
information, but relatively little progress has been made in the treatment of patients with solid …

Background Human cytomegalovirus (HCMV) infection has been actively implicated in
complex neoplastic processes. Beyond oncomodulation, the molecular mechanisms that …

Human cytomegalovirus (HCMV) infection has been implicated in epithelial ovarian cancer
(OC). Polyploidy giant cancer cells (PGCCs) have been observed in high-grade serous …

Human cytomegalovirus (HCMV) is a herpesvirus that alternates lytic and latent infection,
infecting between 40 and 95% of the population worldwide, usually without symptoms …

Docetaxel (DTX) combined with cisplatin and 5-fluorouracil has been used as induction
chemotherapy for head and neck squamous cell carcinoma (HNSCC). However, the …

Simple Summary Even though it is known that (cancer) cells can fuse, it is still less
understood how (cancer) cells merge their plasma membranes, thereby giving rise to bi-and …

Recent data suggest that most genotoxic agents in cancer therapy can lead to shock of
genome and increase in cell size, which leads whole genome duplication or multiplication …

A growing body of evidence is recognizing human cytomegalovirus (HCMV) as a potential
oncogenic virus. We hereby provide the first experimental in vitro evidence for HCMV as a …

Therapeutic resistance represents a major cause of death for most lethal cancers. However,
the underlying mechanisms of such resistance have remained unclear. The polyploid cells …