A basic review on estrogen receptor signaling pathways in breast cancer

L Clusan, F Ferrière, G Flouriot, F Pakdel - International journal of …, 2023 - mdpi.com
Breast cancer is the most common cancer and the deadliest among women worldwide.
Estrogen signaling is closely associated with hormone-dependent breast cancer (estrogen …

Estrogen receptor signaling mechanisms

N Fuentes, P Silveyra - Advances in protein chemistry and structural …, 2019 - Elsevier
The primary female sex hormones, estrogens, are responsible for the control of functions of
the female reproductive system, as well as the development of secondary sexual …

An overview on estrogen receptors signaling and its ligands in breast cancer

MZI Khan, M Uzair, A Nazli, JZ Chen - European Journal of Medicinal …, 2022 - Elsevier
Estrogen governs the regulations of various pathological and physiological actions
throughout the body in both males and females. Generally, 17β-estradiol an endogenous …

Endocrine resistance in hormone receptor positive breast cancer–from mechanism to therapy

A Rani, J Stebbing, G Giamas, J Murphy - Frontiers in endocrinology, 2019 - frontiersin.org
The importance and role of the estrogen receptor (ER) pathway has been well-documented
in both breast cancer (BC) development and progression. The treatment of choice in women …

The impact of estrogen and estrogen-like molecules in neurogenesis and neurodegeneration: beneficial or harmful?

FA Bustamante-Barrientos… - Frontiers in Cellular …, 2021 - frontiersin.org
Estrogens and estrogen-like molecules can modify the biology of several cell types.
Estrogen receptors alpha (ERα) and beta (ERβ) belong to the so-called classical family of …

G protein-coupled estrogen receptor in immune cells and its role in immune-related diseases

G Notas, M Kampa, E Castanas - Frontiers in endocrinology, 2020 - frontiersin.org
G protein-coupled estrogen receptor 1 (GPER1), is a functional estrogen receptor involved
in estrogen related actions on several systems including processes of the nervous …

Expression and role of the G protein-coupled estrogen receptor (GPR30/GPER) in the development and immune response in female reproductive cancers

CD Hernández-Silva, JC Villegas-Pineda… - Frontiers in …, 2020 - frontiersin.org
Cancer is a major public health issue and represents the second leading cause of death in
women worldwide, as female reproductive-related neoplasms are the main cause of …

[HTML][HTML] Raw and salt-processed Achyranthes bidentata attenuate LPS-induced acute kidney injury by inhibiting ROS and apoptosis via an estrogen-like pathway

S Wang, M Zeng, B Li, Y Kan, B Zhang, X Zheng… - Biomedicine & …, 2020 - Elsevier
Abstract Background Traditional Chinese medicine suggests that Radix Achyranthis
Bidentatae nourishes and protects the kidneys, the effect of which is enhanced following a …

Hallmarks of sex bias in immuno-oncology: mechanisms and therapeutic implications

T Xiao, J Lee, TD Gauntner, M Velegraki… - Nature Reviews …, 2024 - nature.com
Sex differences are present across multiple non-reproductive organ cancers, with male
individuals generally experiencing higher incidence of cancer with poorer outcomes …

G-protein coupled estrogen receptor in breast cancer

LH Hsu, NM Chu, YF Lin, SH Kao - International journal of molecular …, 2019 - mdpi.com
The G-protein coupled estrogen receptor (GPER), an alternate estrogen receptor (ER) with a
structure distinct from the two canonical ERs, being ERα, and ERβ, is expressed in 50% to …