Extracellular matrix in uterine leiomyoma pathogenesis: a potential target for future therapeutics

MS Islam, A Ciavattini, F Petraglia… - Human reproduction …, 2018 - academic.oup.com
BACKGROUND Uterine leiomyoma (also known as fibroid or myoma) is the most common
benign tumor of the uterus found in women of reproductive age. It is not usually fatal but can …

[HTML][HTML] Phenolic metabolites as therapeutic in inflammation and neoplasms: Molecular pathways explaining their efficacy

W Liu, X Cui, Y Zhong, R Ma, B Liu, Y Xia - Pharmacological research, 2023 - Elsevier
Polyphenols, also known as phenolic compounds, are chemical substances containing
aromatic rings as well as at least two hydroxyl groups. Natural phenolic compounds exist …

Curcumin nanoformulations: a review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment

O Naksuriya, S Okonogi, RM Schiffelers, WE Hennink - Biomaterials, 2014 - Elsevier
Curcumin, a natural yellow phenolic compound, is present in many kinds of herbs,
particularly in Curcuma longa Linn.(turmeric). It is a natural antioxidant and has shown many …

Curcumin mediates anticancer effects by modulating multiple cell signaling pathways

AB Kunnumakkara, D Bordoloi, C Harsha… - Clinical …, 2017 - portlandpress.com
Curcumin, a component of a spice native to India, was first isolated in 1815 by Vogel and
Pelletier from the rhizomes of Curcuma longa (turmeric) and, subsequently, the chemical …

Curcumin and its topical formulations for wound healing applications

C Mohanty, SK Sahoo - Drug discovery today, 2017 - Elsevier
Highlights•Curcumin has prospective wound-healing activity against chronic wounds.•It has
antioxidant and anti-inflammatory properties.•Restrictive therapeutic role because of poor …

Natural product and natural product derived drugs in clinical trials

MS Butler, AAB Robertson, MA Cooper - Natural product reports, 2014 - pubs.rsc.org
Covering: 2008–2013. Previous review: 2008, 25, 475 There are a significant number of
natural product (NP) drugs in development. We review the 100 NP and NP-derived …

[HTML][HTML] Curcumin-loaded alginate hydrogels for cancer therapy and wound healing applications: A review

A Sood, A Dev, SS Das, HJ Kim, A Kumar… - International journal of …, 2023 - Elsevier
Hydrogels have emerged as a versatile platform for a numerous biomedical application due
to their ability to absorb a huge quantity of biofluids. In order to design hydrogels, natural …

[HTML][HTML] Curcumin: An age-old anti-inflammatory and anti-neoplastic agent

MC Fadus, C Lau, J Bikhchandani, HT Lynch - Journal of traditional and …, 2017 - Elsevier
Curcumin is a natural anti-inflammatory agent that has been used for treating medical
conditions for many years. Several experimental and pharmacologic trials have …

IL-6 and related cytokines as the critical lynchpins between inflammation and cancer

K Taniguchi, M Karin - Seminars in immunology, 2014 - Elsevier
Inflammatory responses play pivotal roles in cancer development, including tumor initiation,
promotion, progression, and metastasis. Cytokines are now recognized as important …

Natural product-based nanomedicine: recent advances and issues

R Watkins, L Wu, C Zhang, RM Davis… - International journal of …, 2015 - Taylor & Francis
Natural products have been used in medicine for many years. Many top-selling
pharmaceuticals are natural compounds or their derivatives. These plant-or microorganism …