Abstract Background The Wnt signaling pathway is a complex network of protein interactions
that functions most commonly in embryonic development and cancer, but is also involved in …

CircRNAs, covalently closed noncoding RNAs, are widely expressed in a wide range of
species ranging from viruses to plants to mammals. CircRNAs were enriched in the Wnt …

Breast cancer is the second common cancer and the leading cause of malignancy among
females overall. Breast cancer stem cells (BCSCs) are a small population of breast cancer …

Simple Summary L-asparaginase (L-ASNase) therapy is key for achieving the very high cure
rate of pediatric acute lymphoblastic leukemia (ALL), yet its use is mostly confined to this …

Background Triple-negative breast cancer (TNBC) is a heterogeneous, aggressive
phenotype of breast cancer with associated chemoresistance. The development of chemo-or …

Triple negative breast cancer (TNBC) is a subtype of breast cancer, with estrogen receptor,
human epidermal growth factor receptor 2 and progesterone receptor negative. TNBC is …

Simple Summary Breast cancer remains the most commonly diagnosed cancer and the
leading cause of cancer death among females worldwide. It is a highly heterogeneous …

Triple-negative breast cancer (TNBC) is not as prevalent as hormone receptor or HER2-
positive breast cancers and all receptor tests come back negative. More importantly, the …

Breast Cancer (BC) is the second most frequent cause of cancer death among women
worldwide and, although there have been significant advances in BC therapies, a significant …

The efficacy of STING (stimulator of interferon genes) agonists is due to various factors,
primarily inefficient intracellular delivery, low/lack of endogenous STING expression in many …