Thalamic contributions to the state and contents of consciousness

CJ Whyte, MJ Redinbaugh, JM Shine, YB Saalmann - Neuron, 2024 - cell.com
Consciousness can be conceptualized as varying along at least two dimensions: the global
state of consciousness and the content of conscious experience. Here, we highlight the …

International Union of Basic and Clinical Pharmacology CXIV: Orexin Receptor Function, Nomenclature and Pharmacology

JP Kukkonen, LH Jacobson, D Hoyer, MK Rinne… - Pharmacological …, 2024 - ASPET
The orexin system consists of the peptide transmitters orexin-A and-B and the G protein-
coupled orexin receptors OX 1 and OX 2. Orexin receptors are capable of coupling to all four …

Correlation between the number of interstitial neurons of the white matter and number of neurons within cortical layers: Histological analyses in postnatal macaque

B Ahmed, A Duque, P Rakic… - Journal of Comparative …, 2024 - Wiley Online Library
We have examined the number and distribution of NeuN‐immunoreactive cortical white
matter interstitial cells (WMICs) and compared them to the neurons in layers 1–6 across the …

Impaired Cognition in Narcolepsy: clinical and neurobiological perspectives

CA Cano, BT Harel, TE Scammell - Sleep, 2024 - academic.oup.com
In addition to well-known symptoms such as sleepiness and cataplexy, many people with
narcolepsy have impaired cognition, reporting inattention, poor memory and other concerns …

[HTML][HTML] Motor Control of Distinct Layer 6 Corticothalamic Feedback Circuits

LE Martinetti, DM Autio, SR Crandall - bioRxiv, 2024 - ncbi.nlm.nih.gov
Abstract Layer 6 corticothalamic (L6 CT) neurons provide massive input to the thalamus, and
these feedback connections enable the cortex to influence its own sensory input by …

Chronic abolition of evoked vesicle release from layer 5 projection neurons disrupts the laminar distribution of parvalbumin interneurons in the adult cortex

FP Szabó, V Sigutova, A Schneider… - bioRxiv, 2024 - biorxiv.org
Establishing precisely built neuronal networks during cortical development requires
appropriate proportions of glutamatergic and GABAergic neurons. Developmental …

FOXP2-immunoreactive, corticothalamic pyramidal cells in neocortical layers 6a and 6b are tightly regulated by neuromodulatory systems

G Qi, D Yang, F Messore, A Bast, F Yáñez… - bioRxiv, 2024 - biorxiv.org
The FOXP2/Foxp2 gene is involved in fine motor control in many vertebrate species; in
humans, it is one of the candidate genes thought to play a prominent role in language …

Spatial mRNA expression patterns of orexin receptors in the dorsal hippocampus

GM Krause, LM Chirich Barreira, A Albrecht - bioRxiv, 2024 - biorxiv.org
Orexins are wake-promoting neuropeptides that originate from hypothalamic neurons
projecting to widespread brain areas throughout the central nervous system. They modulate …