[HTML][HTML] Nanopore sequencing technology, bioinformatics and applications

Y Wang, Y Zhao, A Bollas, Y Wang, KF Au - Nature biotechnology, 2021 - nature.com
Rapid advances in nanopore technologies for sequencing single long DNA and RNA
molecules have led to substantial improvements in accuracy, read length and throughput …

[HTML][HTML] Genetics and genomics of SARS-CoV-2: A review of the literature with the special focus on genetic diversity and SARS-CoV-2 genome detection

A Rahimi, A Mirzazadeh, S Tavakolpour - Genomics, 2021 - Elsevier
The outbreak of 2019-novel coronavirus disease (COVID-19), caused by SARS-CoV-2,
started in late 2019; in a short time, it has spread rapidly all over the world. Although some …

[HTML][HTML] The coding capacity of SARS-CoV-2

Y Finkel, O Mizrahi, A Nachshon… - Nature, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing
coronavirus disease 2019 (COVID-19) pandemic 1. To understand the pathogenicity and …

Human leukocyte antigen susceptibility map for severe acute respiratory syndrome coronavirus 2

A Nguyen, JK David, SK Maden, MA Wood… - Journal of …, 2020 - Am Soc Microbiol
Genetic variability across the three major histocompatibility complex (MHC) class I genes
(human leukocyte antigen A [HLA-A],-B, and-C genes) may affect susceptibility to and …

[HTML][HTML] Genome-wide analysis of SARS-CoV-2 virus strains circulating worldwide implicates heterogeneity

MR Islam, MN Hoque, MS Rahman, ASMRU Alam… - Scientific reports, 2020 - nature.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a novel evolutionary
divergent RNA virus, is responsible for the present devastating COVID-19 pandemic. To …

Temporal signal and the phylodynamic threshold of SARS-CoV-2

S Duchene, L Featherstone… - Virus …, 2020 - academic.oup.com
The ongoing SARS-CoV-2 outbreak marks the first time that large amounts of genome
sequence data have been generated and made publicly available in near real time. Early …

[HTML][HTML] COVID-19 in health-care workers in three hospitals in the south of the Netherlands: a cross-sectional study

RS Sikkema, SD Pas, DF Nieuwenhuijse… - The Lancet Infectious …, 2020 - thelancet.com
Background 10 days after the first reported case of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection in the Netherlands (on Feb 27, 2020), 55 (4%) of …

[HTML][HTML] Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy

E Wyler, K Mösbauer, V Franke, A Diag, LT Gottula… - IScience, 2021 - cell.com
Detailed knowledge of the molecular biology of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection is crucial for understanding of viral replication, host …

[HTML][HTML] Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug …

D Butler, C Mozsary, C Meydan, J Foox… - Nature …, 2021 - nature.com
In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) killed over a million people, including> 25,000 in New York City (NYC) alone. The …

Nanopore targeted sequencing for the accurate and comprehensive detection of SARS‐CoV‐2 and other respiratory viruses

M Wang, A Fu, B Hu, Y Tong, R Liu, Z Liu, J Gu… - Small, 2020 - Wiley Online Library
The ongoing global novel coronavirus pneumonia COVID‐19 outbreak has engendered
numerous cases of infection and death. COVID‐19 diagnosis relies upon nucleic acid …