Cryptococcus neoformans and Cryptococcus gattii are the two etiologic agents of
cryptococcosis. They belong to the phylum Basidiomycota and can be readily distinguished …

Among fungal pathogens, Cryptococcus neoformans has gained great importance among
the scientific community of several reasons. This fungus is the causative agent of …

Metals are essential for life, and they play a central role in the struggle between infecting
microbes and their hosts. In fact, an important aspect of microbial pathogenesis is the …

Cryptococcus spp. are environmental fungi that first must adapt to the host environment
before they can cause life-threatening meningitis in immunocompromised patients. Host …

Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …

Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses.
However, mechanisms of Th2 cell accumulation are multifactorial and incompletely known …

The importance of the Basidiomycete Cryptococcus neoformans to human health has
stimulated its development as an experimental model for both basic physiology and …

Highlights•Cryptococcus has an unusual morphological transition in vivo to generate
enlarged titan cells.•Titan cells are greater than 15 μm in diameter, have a thick cell wall …