A ternary amorphous solid dispersion (ASD) system consisting of drug/polymer/surfactant is
receiving increased attention to improve the oral bioavailability of poorly water-soluble …

Atorvastatin is a statin group HMG-CoA reductase inhibitor drug that is commonly used to
adverse cardiovascular events and to lower blood total cholesterol and LDL-cholesterol. In …

Oral drugs present the most convenient, economical, and painless route for self-
administration. Despite commercialization of multiple technologies relying on micro-and …

It is well established that polymers adopt a range of conformations and solution-state
organization in response to varying solution environments, although very little work has …

Background: Administering Cinacalcet HCl (CINA) can be challenging because of its low
oral bioavailability (20 to 25%) due mainly to its high first-pass metabolism and poor …

To prevent the sticking of Corni fructus extract (CFE) during spray drying, the anti-sticking
effects of different excipients were compared. Hydroxypropyl methylcellulose (HPMC)-VLV …

Thanks to the recent developments in nanotechnology, there have been great advances in
the field of nanomedicine. Development of nanotherapeutics and related therapies based on …

To enhance oral bioavailability of poorly soluble drugs, microfabricated devices can be
utilized. One example of such devices is microcontainers. These are cylindrical in shape …

The extracts of Spondias mombin leaves were obtained to study the influence of drug
amount and ethanol proportion on extract performance. The optimized extract was dried by …

Felodipine has been widely used as a poorly water-soluble model drug for various studies to
improve its oral bioavailability and in vivo efficacy. In this study, we developed amorphous …