There are currently eight different classes of drugs available for lowering cholesterol levels.
There are currently seven HMG-CoA reductase inhibitors (statins) approved for lowering …

Cardiac abnormalities were identified early in the epidemic of AIDS, predating the isolation
and characterization of the etiologic agent, HIV. Several decades later, the causation and …

Importance Despite higher atherosclerotic cardiovascular disease (ASCVD) risk, people with
HIV (PWH) experience unique barriers to ASCVD prevention, such as changing models of …

Background Previous meta-analyses of summary data from randomised controlled trials
have shown that statin therapy increases the risk of diabetes, but less is known about the …

HIV type 1 (HIV-1) is the causative agent of AIDS. Since the start of the epidemic, HIV/AIDS
has been responsible for≈ 40 million deaths. Additionally, an estimated 39 million people …

HIV infection and antiretroviral therapy alter mitochondrial function, which can progressively
lead to mitochondrial damage and accelerated aging. The interaction between persistent …

People living with HIV have a 1.5-to 2-fold increased risk of developing cardiovascular
disease. Despite treatment with highly effective antiretroviral therapy, people living with HIV …

Given advances in antiretroviral therapy, the mortality rate for HIV infection has dropped
considerably over recent decades. However, people living with HIV (PLWH) experience …

Cumulative exposure to low-density lipoprotein cholesterol (LDL-C) is a key driver of
atherosclerotic cardiovascular disease (ASCVD) risk. An armamentarium of therapies to …

Contemporary World Health Organization data indicates that≈ 39 million people are living
with the human immunodeficiency virus. Of these, 24 million have been reported to have …