[HTML][HTML] Traumatic brain injury: progress and challenges in prevention, clinical care, and research
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
Management of moderate to severe traumatic brain injury: an update for the intensivist
G Meyfroidt, P Bouzat, MP Casaer, R Chesnut… - Intensive care …, 2022 - Springer
Traumatic brain injury (TBI) remains one of the most fatal and debilitating conditions in the
world. Current clinical management in severe TBI patients is mainly concerned with …
world. Current clinical management in severe TBI patients is mainly concerned with …
Severe traumatic brain injury: targeted management in the intensive care unit
Severe traumatic brain injury (TBI) is currently managed in the intensive care unit with a
combined medical–surgical approach. Treatment aims to prevent additional brain damage …
combined medical–surgical approach. Treatment aims to prevent additional brain damage …
[HTML][HTML] Serum neurofilament light protein predicts clinical outcome in traumatic brain injury
P Shahim, M Gren, V Liman, U Andreasson… - Scientific reports, 2016 - nature.com
Axonal white matter injury is believed to be a major determinant of adverse outcomes
following traumatic brain injury (TBI). We hypothesized that measurement of neurofilament …
following traumatic brain injury (TBI). We hypothesized that measurement of neurofilament …
[HTML][HTML] Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury
Objective We aimed to explore the added value of common machine learning (ML)
algorithms for prediction of outcome for moderate and severe traumatic brain injury. Study …
algorithms for prediction of outcome for moderate and severe traumatic brain injury. Study …
Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
Executive summary A concerted effort to tackle the global health problem posed by traumatic
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …
Early management of severe traumatic brain injury
Severe traumatic brain injury remains a major health-care problem worldwide. Although
major progress has been made in understanding of the pathophysiology of this injury, this …
major progress has been made in understanding of the pathophysiology of this injury, this …
[HTML][HTML] Clustering identifies endotypes of traumatic brain injury in an intensive care cohort: a CENTER-TBI study
Abstract Background While the Glasgow coma scale (GCS) is one of the strongest outcome
predictors, the current classification of traumatic brain injury (TBI) as 'mild','moderate'or …
predictors, the current classification of traumatic brain injury (TBI) as 'mild','moderate'or …
Persistent problems 1 year after mild traumatic brain injury: a longitudinal population study in New Zealand
Background Mild traumatic brain injury (mTBI) is a common problem in general practice
settings, yet previous research does not take into account those who do not attend hospital …
settings, yet previous research does not take into account those who do not attend hospital …
[HTML][HTML] Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury
H Wang, XM Zhou, LY Wu, GJ Liu, WD Xu… - Journal of …, 2020 - Springer
Abstract Background Aucubin (Au), an iridoid glycoside from natural plants, has
antioxidative and anti-inflammatory bioactivities; however, its effects on a traumatic brain …
antioxidative and anti-inflammatory bioactivities; however, its effects on a traumatic brain …