Anti-oxidant and anti-inflammatory effects of astaxanthin on gastrointestinal diseases

J Lee, MH Kim, H Kim - International journal of molecular sciences, 2022 - mdpi.com
A moderate amount of reactive oxygen species (ROS) is produced under normal conditions,
where they play an important role in cell signaling and are involved in many aspects of the …

[HTML][HTML] Natural products for combating multidrug resistance in cancer

T Chen, Z Xiao, X Liu, T Wang, Y Wang, F Ye… - Pharmacological …, 2024 - Elsevier
Cancer cells frequently develop resistance to chemotherapeutic therapies and targeted
drugs, which has been a significant challenge in cancer management. With the growing …

Natural products targeting signaling pathways associated with regulated cell death in gastric cancer: Recent advances and perspectives

Q Hu, Z Li, Y Li, X Deng, Y Chen, X Ma… - Phytotherapy …, 2023 - Wiley Online Library
Gastric cancer (GC) is one of the most serious gastrointestinal malignancies with high
morbidity and mortality. The complexity of GC process lies in the multi‐phenotypic linkage …

Research progress on biological regulation and biosynthesis of isosteroid alkaloids in Fritillaria

P Qi, Y Zhang, C Zhao, L Sun, R Bai, L Wang… - Plant Growth …, 2023 - Springer
Isosteroidal alkaloids are kinds of alkaloids with unique structures and remarkable activities.
These compounds have important pharmacological activities, such as analgesic …

Botanical characterization, phytochemistry, biosynthesis, pharmacology clinical application, and breeding techniques of the Chinese herbal medicine Fritillaria …

Y Zhang, H Han, D Li, Y Fan, M Liu, H Ren… - Frontiers in …, 2024 - frontiersin.org
Fritillaria unibracteata (FRU) belongs to the genus Fritillaria of the Liliaceae family. It is one
of the original plants of the Chinese medicinal material “Chuanbeimu” and also a biological …

Network pharmacology and experimental validation for deciphering the action mechanism of Fritillaria cirrhosa D. Don constituents in suppressing breast carcinoma

BA Bhat, W Rashid Mir, M Alkhanani… - Journal of …, 2023 - Taylor & Francis
Fritillaria cirrhosa D. Don is a well-known medicinal plant of Kashmir Himalaya. Traditionally,
it has been used to treat several diseases, including cancer. However, the molecular …

The recent update and advancements of natural products in targeting the Wnt/β-Catenin pathway for cancer prevention and therapeutics

L Saikia, B Gogoi, S Sen, RK Tonk, D Kumar, PP Dutta - Medical Oncology, 2024 - Springer
Abstract The Wnt/β-Catenin pathway (Wnt/β-CatP) is implicated in accelerating
carcinogenesis and cancer progression, contributing to increased morbidity and treatment …

Crosstalk between CXCL12/CXCR4/ACKR3 and the STAT3 Pathway

Z Ma, F Zhou, H Jin, X Wu - Cells, 2024 - mdpi.com
The reciprocal modulation between the CXCL12/CXCR4/ACKR3 axis and the STAT3
signaling pathway plays a crucial role in the progression of various diseases and …

Peimine induces apoptosis of glioblastoma cells through regulation of the PI3K/AKT signaling pathway

J Lei, J Yang, S Cheng, F Lu, Z Wu… - Experimental and …, 2024 - spandidos-publications.com
Glioblastoma (GBM) is one of the most malignant forms of intracranial tumors, with high
mortality rates and invariably poor prognosis, due to the limited clinical treatment strategies …

Integrated study of HR-LC/MS and network pharmacology to identify breast cancer-related molecular targets of Fritillaria cirrhosa D. Don active constituents in …

BA Bhat, WR Mir, M Alkhanani, A Almilaibary, MA Mir - 2023 - researchsquare.com
Fritillaria cirrhosa D. Don is a well-known medicinal plant in Kashmir Himalya. Traditionally,
it has been used to treat several diseases, most notably in the treatment of various cancers …