The cellular membrane constitutes one of the most fundamental compartments of a living
cell, where key processes such as selective transport of material and exchange of …

The plasma membrane of eukaryotic cells contains several types of lipids displaying high
biochemical variability in both their apolar moiety (eg, the acyl chain of glycerolipids) and …

For some membrane proteins, detergent-mediated solubilization compromises protein
stability and functionality, often impairing biophysical and structural analyses. Hence …

A better understanding of the cellular physiological role that plasma membrane lipids, fatty
acids and sterols play in various cellular systems may yield more insight into how cellular …

The membrane bilayer has a significant influence over the proteins embedded within it. G
protein-coupled receptors (GPCRs) form a large group of membrane proteins with a vast …

Are lipid interactions with membrane proteins best described in terms of the physical
properties of the lipid bilayer or in terms of direct molecular interactions between particular …

Like all other monomeric or multimeric transmembrane proteins, receptors for
neurotransmitters are surrounded by a shell of lipids which form an interfacial boundary …

Atomic-resolution structural studies of membrane-associated proteins and peptides in a
membrane environment are important to fully understand their biological function and the …

G protein-coupled receptors (GPCRs) are the largest class of molecules involved in signal
transduction across cell membranes and represent major targets in the development of …

Cholesterol is an essential component of higher eukaryotic membranes and plays a crucial
role in membrane organization, dynamics and function. The G-protein coupled receptors …