Fibrosis is the abnormal accumulation of extracellular matrix proteins such as collagen and
fibronectin. Aging, injury, infections, and inflammation can cause different types of tissue …

Membranous nephropathy (MN) is one of the most common causes of non-diabetic
nephrotic syndrome in adults. About 80% of cases are renal limited (primary MN) and 20 …

As epigenetic modifications, lactylation and N6-methyladenosine (m6A) have attracted wide
attention. Arsenite is an environmental pollutant that has been proven to induce idiopathic …

Fucoidan is a native sulfated polysaccharide mainly isolated from brown seaweed, with
diverse pharmacological activities, such as anti-inflammatory and antifibrosis …

Fibrosis is a typical aging-related pathological process involving almost all organs, including
the heart, kidney, liver, lung, and skin. Fibrogenesis is a highly orchestrated process defined …

Membranous nephropathy (MN) patients are diagnosed by the presence of phospholipase A
2 receptor (PLA2R) before they progress to renal failure. However, the subepithelium-like …

Renal fibrosis is increasingly recognized as a global public health problem. Acute kidney
injury (AKI) and chronic kidney disease (CKD) both result in renal fibrosis. Oxidative stress …

Peritoneal dialysis is an efficient renal replacement therapy for patients with end-stage
kidney disease. However, continuous exposure of the peritoneal membrane to dialysate …

Homeostasis constitutes a key concept in physiology and refers to self‐regulating processes
that maintain internal stability when adjusting to changing external conditions. It diminishes …

The liver possesses a unique regenerative ability to restore its original mass, in this regard,
partial hepatectomy (PHx) and partial liver transplantation (PLTx) can be executed smoothly …