New therapeutic strategies in systemic lupus erythematosus management
M Gatto, M Zen, L Iaccarino, A Doria - Nature Reviews Rheumatology, 2019 - nature.com
The current treatment approach for systemic lupus erythematosus (SLE), as outlined in the
recommendations by international medical associations including EULAR and the ACR, is …
recommendations by international medical associations including EULAR and the ACR, is …
2019 update of the EULAR recommendations for the management of systemic lupus erythematosus
A Fanouriakis, M Kostopoulou, A Alunno… - Annals of the …, 2019 - ard.bmj.com
Our objective was to update the EULAR recommendations for the management of systemic
lupus erythematosus (SLE), based on emerging new evidence. We performed a systematic …
lupus erythematosus (SLE), based on emerging new evidence. We performed a systematic …
Conceptual framework for defining disease modification in systemic lupus erythematosus: a call for formal criteria
R van Vollenhoven, AD Askanase… - Lupus science & …, 2022 - lupus.bmj.com
Disease modification has become a well-established concept in several therapeutic areas;
however, no widely accepted definition of disease modification exists for SLE. We reviewed …
however, no widely accepted definition of disease modification exists for SLE. We reviewed …
Lupus low disease activity state is associated with a decrease in damage progression in Caucasian patients with SLE, but overlaps with remission
M Zen, L Iaccarino, M Gatto, F Saccon… - Annals of the …, 2018 - ard.bmj.com
Objective To evaluate the prevalence, duration and effect on damage accrual of the 'Lupus
Low Disease Activity State'(LLDAS) in a monocentric cohort of patients with systemic lupus …
Low Disease Activity State'(LLDAS) in a monocentric cohort of patients with systemic lupus …
Early disease and low baseline damage as predictors of response to belimumab in patients with systemic lupus erythematosus in a real‐life setting
M Gatto, F Saccon, M Zen, F Regola… - Arthritis & …, 2020 - Wiley Online Library
Objective To investigate predictors of response, remission, low disease activity, damage,
and drug discontinuation in patients with systemic lupus erythematosus (SLE) who were …
and drug discontinuation in patients with systemic lupus erythematosus (SLE) who were …
Remission and Low Disease Activity Status (LDAS) protect lupus patients from damage occurrence: data from a multiethnic, multinational Latin American Lupus …
MF Ugarte-Gil, D Wojdyla, GJ Pons-Estel… - Annals of the …, 2017 - ard.bmj.com
Objective To evaluate disease activity statuses'(DAS') impact on systemic lupus
erythematosus (SLE) outcomes. Materials and methods Four DAS were defined: remission …
erythematosus (SLE) outcomes. Materials and methods Four DAS were defined: remission …
Systemic Lupus Erythematosus Disease Activity Score (SLE-DAS) enables accurate and user-friendly definitions of clinical remission and categories of disease …
D Jesus, M Larosa, C Henriques, A Matos… - Annals of the …, 2021 - ard.bmj.com
Objectives There is an unmet need for accurate and user-friendly definitions of systemic
lupus erythematosus (SLE) disease activity and remission. We aimed to derive and validate …
lupus erythematosus (SLE) disease activity and remission. We aimed to derive and validate …
Lupus low disease activity state and remission and risk of mortality in patients with systemic lupus erythematosus: a prospective, multinational, longitudinal cohort …
R Kandane-Rathnayake, V Golder… - The Lancet …, 2022 - thelancet.com
Background Treat-to-target goals for patients with systemic lupus erythematosus (SLE) have
been validated to protect against organ damage and to improve quality of life. We aimed to …
been validated to protect against organ damage and to improve quality of life. We aimed to …
TNF-α and plasma albumin as biomarkers of disease activity in systemic lupus erythematosus
H Idborg, S Eketjäll, S Pettersson… - Lupus Science & …, 2018 - lupus.bmj.com
Objectives Composite criteria/indices are presently used to diagnose and monitor patients
with systemic lupus erythematosus (SLE). Biomarkers for these purposes would be helpful in …
with systemic lupus erythematosus (SLE). Biomarkers for these purposes would be helpful in …
Remission and low disease activity (LDA) prevent damage accrual in patients with systemic lupus erythematosus: results from the Systemic Lupus International …
MF Ugarte-Gil, J Hanly, M Urowitz, C Gordon… - Annals of the …, 2022 - ard.bmj.com
Objective To determine the independent impact of different definitions of remission and low
disease activity (LDA) on damage accrual. Methods Patients with≥ 2 annual assessments …
disease activity (LDA) on damage accrual. Methods Patients with≥ 2 annual assessments …