Background Remission and low disease activity (LDA) have been proposed as the treatment
goals for patients with systemic lupus erythematosus (SLE). Several definitions for each …

Objectives To evaluate what proportion of patients fulfil the DORIS definition of remission,
the definition of lupus low disease activity state (LLDAS) and LLDAS with a glucocorticoid …

Objective To achieve a consensus-based definition of Low Disease Activity (LDA) for use in
cSLE trials. Methods The International cSLE T2T Task Force, comprising of paediatric …

Abstract Background Systemic sclerosis (SSc) is a rare autoimmune disease characterized
by fibrosis of the skin and the involvement of multiple internal organs. Previous studies …

Objectives To assess the achievability and effect of attaining low disease activity (LDA) or
remission in childhood-onset SLE (cSLE). Methods Attainment of three adult-SLE derived …

Objectives Remission in systemic lupus erythematosus (SLE) is defined through a
combination of 'clinical SLE Disease Activity Index (cSLEDAI)= 0','physician's global …

SLE poses formidable therapeutic challenges due to its heterogeneity and treatment
decisions often cannot be guided by data of high quality. In this review, we attempt to …

Abstract Systemic Lupus Erythematosus is a systemic autoimmune disease characterized by
a great heterogenicity in course and clinical manifestations. Although prognosis improved in …

Background: Total glucosides of paeony (TGP), extracted from the dried roots of Paeonia
lactiflora Pall., are proven to regulate immune function in various rheumatic diseases. We …

Thoracic diseases in patients with systemic lupus erythematosus (SLE), especially interstitial
pneumonia (SLE-IP), are rare and have been poorly studied. The aims of this multicentre …