Current controversies in low-risk differentiated thyroid cancer: reducing overtreatment in an era of overdiagnosis

TM Ullmann, M Papaleontiou… - The Journal of Clinical …, 2023 - academic.oup.com
Context Low-risk differentiated thyroid cancer (DTC) is overdiagnosed, but true incidence
has increased as well. Owing to its excellent prognosis with low morbidity and mortality …

Management of Advanced Thyroid Cancer: Overview, Advances, and Opportunities

S Agosto Salgado, ER Kaye, Z Sargi… - American Society of …, 2023 - ascopubs.org
Thyroid cancer is the most common endocrine malignancy with almost one million people
living with thyroid cancer in the United States. Although early-stage well-differentiated …

Inflammatory cytokine-regulated LNCPTCTS suppresses thyroid cancer progression via enhancing Snail nuclear export

C Ma, N Zhang, T Wang, H Guan, Y Huang, L Huang… - Cancer Letters, 2023 - Elsevier
Lymph node metastases are commonly observed in diverse malignancies where they
promote cancer progression and poor outcomes, although the molecular basis is …

Disease-specific survival trends for patients presenting with differentiated thyroid cancer and distant metastases in the United States, 1992–2018

A Wilhelm, PC Conroy, L Calthorpe, AM Shui… - Thyroid, 2023 - liebertpub.com
Objective: Differentiated thyroid cancer (DTC) is associated with an excellent prognosis, but
patients with distant metastatic DTC have a 10-year disease-specific survival (DSS) of just …

Five-year outcome between radiofrequency ablation vs surgery for unilateral multifocal papillary thyroid microcarcinoma

L Yan, Z Yang, Y Li, X Li, J Xiao… - The Journal of Clinical …, 2023 - academic.oup.com
Context Ultrasound (US)-guided radiofrequency ablation (RFA) has been considered as an
alternative to surgery or active surveillance for papillary thyroid microcarcinoma (PTMC) …

Racial and ethnic disparities in appropriate thyroid cancer treatment, before and after the release of the 2015 American Thyroid Association Guidelines

SP Ginzberg, JM Soegaard Ballester… - Annals of Surgical …, 2023 - Springer
Abstract Background The 2015 American Thyroid Association (ATA) guidelines reduced the
recommended extent of therapy for low-risk thyroid cancers. Little is known about the impact …

Endocrine surgeons are performing more thyroid lobectomies for low-risk differentiated thyroid cancer since the 2015 ATA guidelines

PC Conroy, A Wilhelm, L Calthorpe, TM Ullmann… - Surgery, 2022 - Elsevier
Abstract Background The 2015 American Thyroid Association guidelines recommended
either total thyroidectomy or lobectomy for surgical treatment of low-risk differentiated thyroid …

Partial thyroidectomy with incidental metastatic lymph nodes

E Alameer, A Eagan, DW Scholfield… - … –Head & Neck …, 2024 - jamanetwork.com
Importance The need for completion thyroidectomy in patients with incidental metastatic
lymph nodes after partial thyroidectomy is unclear. Objective To investigate the outcomes of …

Sonographic evolution and pathologic findings of papillary thyroid cancer after radiofrequency ablation: a five-year retrospective cohort study

X Li, Y Li, L Yan, J Xiao, Z Yang, H Jing, M Zhang… - Thyroid, 2024 - liebertpub.com
Background: The criteria for determining technical efficacy of thermal ablation for papillary
thyroid carcinoma (PTC) are not clearly defined. We analyzed the involution process of the …

Prognostic value of preoperative molecular testing and implications for initial surgical management in thyroid nodules harboring suspected (Bethesda V) or known …

MA Schumm, ML Shu, EG Hughes… - … –head & neck …, 2023 - jamanetwork.com
Importance Molecular testing is commonly used in the diagnosis of thyroid nodules with
indeterminate cytology. The role of molecular testing in prognosticating oncologic outcomes …