Liquid biopsy: a step forward towards precision medicine in urologic malignancies

A Di Meo, J Bartlett, Y Cheng, MD Pasic, GM Yousef - Molecular cancer, 2017 - Springer
There is a growing trend towards exploring the use of a minimally invasive “liquid biopsy” to
identify biomarkers in a number of cancers, including urologic malignancies. Multiple …

Clinical applications of the CellSearch platform in cancer patients

S Riethdorf, L O'Flaherty, C Hille, K Pantel - Advanced drug delivery …, 2018 - Elsevier
Abstract The CellSearch® system (CS) enables standardized enrichment and enumeration
of circulating tumor cells (CTCs) that are repeatedly assessable via non-invasive “liquid …

Updated 2016 EAU guidelines on muscle-invasive and metastatic bladder cancer

JA Witjes, T Lebret, EM Compérat, NC Cowan… - European urology, 2017 - Elsevier
Context Invasive bladder cancer is a frequently occurring disease with a high mortality rate
despite optimal treatment. The European Association of Urology (EAU) Muscle-invasive and …

The biological complexity of urothelial carcinoma: Insights into carcinogenesis, targets and biomarkers of response to therapeutic approaches

PD Grivas, M Melas, AG Papavassiliou - Seminars in cancer biology, 2015 - Elsevier
Bladder cancer is a major cause of morbidity, mortality and health-related costs. Urothelial
carcinoma is by far the most common histologic type of bladder cancer and may also arise …

Prognostic role and HER2 expression of circulating tumor cells in peripheral blood of patients prior to radical cystectomy: a prospective study

M Rink, FK Chun, R Dahlem, A Soave, S Minner… - European urology, 2012 - Elsevier
BACKGROUND: Preliminary research has suggested the potential prognostic value of
circulating tumor cells (CTC) in patients with advanced nonmetastatic urothelial carcinoma …

Role of exosomal miRNA in bladder cancer: a promising liquid biopsy biomarker

XM Piao, EJ Cha, SJ Yun, WJ Kim - International journal of molecular …, 2021 - mdpi.com
Bladder cancer (BCa) is the most prevalent neoplasia of the urinary tract. Unfortunately,
limited improvements in effective BCa management have meant that it remains a …

Circulating tumor cells as predictive and prognostic biomarkers in solid tumors

M Capuozzo, F Ferrara, M Santorsola, A Zovi… - Cells, 2023 - mdpi.com
Circulating tumor cells (CTCs) have emerged as pivotal biomarkers with significant
predictive and prognostic implications in solid tumors. Their presence in peripheral blood …

Bladder cancer detection and monitoring: assessment of urine-and blood-based marker tests

S Goodison, CJ Rosser, V Urquidi - Molecular diagnosis & therapy, 2013 - Springer
Bladder cancer is one of the most prevalent cancers worldwide, but the treatment and
management of this disease can be very successful if the disease is detected early. The …

Liquid biopsy biomarkers in bladder cancer: a current need for patient diagnosis and monitoring

I Lodewijk, M Dueñas, C Rubio… - International journal of …, 2018 - mdpi.com
Bladder Cancer (BC) represents a clinical and social challenge due to its high incidence
and recurrence rates, as well as the limited advances in effective disease management …

[HTML][HTML] Next-generation sequencing (NGS) of cell-free circulating tumor DNA and tumor tissue in patients with advanced urothelial cancer: a pilot assessment of …

PC Barata, VS Koshkin, P Funchain, D Sohal… - Annals of …, 2017 - Elsevier
Background Advances in cancer genome sequencing have led to the development of
various next-generation sequencing (NGS) platforms. There is paucity of data regarding …