Brain aquaporins facilitate the movement of water between the four water compartments:
blood, cerebrospinal fluid, interstitial fluid, and intracellular fluid. This work analyzes the …

Since the discovery of a specific autoantibody in patients with neuromyelitis optica spectrum
disorder (NMOSD) in 2004, the water channel aquaporin-4 (AQP4) has attracted attention as …

Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory demyelinating disease
of the central nervous system (CNS). Our previous study indicated that neutrophil-related …

Optic neuritis (ON) in neuromyelitis optica spectrum disorders (NMOSD) regularly leads to
more profound vision loss compared to multiple sclerosis (MS) and myelin-oligodendrocyte …

The retina is part of the central nervous system specialized for vision. Inherited retinal
diseases (IRD) are a group of clinically and genetically heterogenous disorders that lead to …

Neuromyelitis optica (NMO) is a rare autoimmune inflammatory disorder affecting the central
nervous system (CNS), specifically the optic nerve and the spinal cord, with severe clinical …

The retinal neurovascular unit (NVU) is paramount to maintaining the homeostasis of the
retina and determines the progression of various diseases, including diabetic retinopathy …

Diabetic retinopathy (DR) is a common microvascular complication that causes visual
impairment or loss. Aquaporin 4 (AQP4) is a regulatory protein involved in water transport …

Diabetic retinopathy (DR), a leading cause of visual impairment, demands a profound
comprehension of its cellular mechanisms to formulate effective therapeutic strategies. Our …

Neuromyelitis optica spectrum disorders (NMOSD) are chronic inflammatory diseases of the
central nervous system, characterized by autoantibodies against aquaporin-4. The …