[HTML][HTML] Emerging Innate Immune Cells in Cancer Immunotherapy: Promises and Challenges
J Wu - BioDrugs, 2024 - Springer
Immune checkpoint inhibitor (ICI)-based therapy has made an unprecedented impact on
survival benefit for a subset of cancer patients; however, only a subset of cancer patients is …
survival benefit for a subset of cancer patients; however, only a subset of cancer patients is …
Gene-modified NK Cells Expressing CD64 and Pre-loaded with HIV-specific BNAbs Target Autologous HIV-1 Infected CD4+ T Cells by ADCC
C Tomescu, AO Ortiz, LD Lu, H Kong, JL Riley… - bioRxiv, 2024 - biorxiv.org
NK cells can efficiently mediate antibody-dependent cellular cytotoxicity (ADCC) of antibody
coated target cells via the low-affinity Fc-receptor, CD16, but cannot retain antibodies over …
coated target cells via the low-affinity Fc-receptor, CD16, but cannot retain antibodies over …
Enhanced IL-15-mediated NK cell activation and proliferation by an ADAM17 function-blocking antibody involves CD16A, CD137, and accessory cells
Background. NK cells are being extensively studied as a cell therapy for cancer. Their
effector functions are induced by the recognition of ligands on tumor cells and by various …
effector functions are induced by the recognition of ligands on tumor cells and by various …