[HTML][HTML] Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications
CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
[HTML][HTML] Synaptic neurexin complexes: a molecular code for the logic of neural circuits
TC Südhof - Cell, 2017 - cell.com
Synapses are specialized junctions between neurons in brain that transmit and compute
information, thereby connecting neurons into millions of overlapping and interdigitated …
information, thereby connecting neurons into millions of overlapping and interdigitated …
[HTML][HTML] Genetics of glutamate and its receptors in autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental impairment characterized by
deficits in social interaction skills, impaired communication, and repetitive and restricted …
deficits in social interaction skills, impaired communication, and repetitive and restricted …
Advancing the understanding of autism disease mechanisms through genetics
Progress in understanding the genetic etiology of autism spectrum disorders (ASD) has
fueled remarkable advances in our understanding of its potential neurobiological …
fueled remarkable advances in our understanding of its potential neurobiological …
Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma
HS Venkatesh, LT Tam, PJ Woo, J Lennon, S Nagaraja… - Nature, 2017 - nature.com
High-grade gliomas (HGG) are a devastating group of cancers, and represent the leading
cause of brain tumour-related death in both children and adults. Therapies aimed at …
cause of brain tumour-related death in both children and adults. Therapies aimed at …
Autism spectrum disorder: neuropathology and animal models
M Varghese, N Keshav, S Jacot-Descombes… - Acta …, 2017 - Springer
Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An …
integration of affected individuals and is the most heritable of psychiatric disorders. An …
Hippocampal GABAergic inhibitory interneurons
KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …
of the total neuronal population; however, their remarkable anatomical and physiological …
Reconsidering animal models used to study autism spectrum disorder: Current state and optimizing future
Neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based …
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based …
[HTML][HTML] Synaptopathology involved in autism spectrum disorder
Autism spectrum disorder (ASD) encompasses a group of multifactorial neurodevelopmental
disorders characterized by impaired social communication, social interaction and repetitive …
disorders characterized by impaired social communication, social interaction and repetitive …
[HTML][HTML] FOXG1-dependent dysregulation of GABA/glutamate neuron differentiation in autism spectrum disorders
Autism spectrum disorder (ASD) is a disorder of brain development. Most cases lack a clear
etiology or genetic basis, and the difficulty of re-enacting human brain development has …
etiology or genetic basis, and the difficulty of re-enacting human brain development has …