Air pollution is one of the serious problems world is facing in recent Anthropocene era of
rapid industrialization and urbanization. Specifically particulate matter (PM) pollution …

Epidemiological studies demonstrated an association between increased levels of ambient
air pollution particles and human morbidity and mortality. Production of oxidants, either …

Generation of oxidatively damaged DNA by particulate matter (PM) is hypothesized to occur
via production of reactive oxygen species (ROS) and inflammation. We investigated this …

Air pollution, especially airborne particulate matter (PM), is associated with an increase in
both morbidity and mortality from cardiovascular disease, although the underlying …

The development of a rodent ambient particulate matter (PM) inhalation system is critical for
drawing causal inferences between PM exposure and the onset of human diseases. In this …

Background Altered patterns of gene expression mediate the effects of particulate matter
(PM) on human health, but mechanisms through which PM modifies gene expression are …

Epidemiological studies of the past decades have provided a strong body of evidence that
elevated levels of ambient particulate air pollution (PM) are associated with increased …

Sensing of pathogens by specialized receptors is the hallmark of the innate immunity. Innate
immune response also mounts a defense response against various allergens and pollutants …

Several studies have shown that particles of smaller size may be more potent than larger to
induce inflammatory and toxic responses in cultured lung cells. However, the relative …

Our group was the first one reporting that autophagy could be triggered by airborne fine
particulate matter (PM) with a mean diameter of less than 2.5 μm (PM 2.5) in human lung …