Cyclic nucleotide phosphodiesterase 3A–deficient mice as a model of female infertility

S Masciarelli, K Horner, C Liu, SH Park… - The Journal of …, 2004 - Am Soc Clin Investig
Since cAMP blocks meiotic maturation of mammalian and amphibian oocytes in vitro and
cyclic nucleotide phosphodiesterase 3A (PDE3A) is primarily responsible for oocyte cAMP …

Gene expression profile of cumulus cells derived from cumulus–oocyte complexes matured either in vivo or in vitro

D Tesfaye, N Ghanem, F Carter, T Fair… - Reproduction …, 2009 - CSIRO Publishing
Although it is well established that maturation conditions have a clear influence on oocyte
developmental competence, it is not known whether this could be due to downstream effects …

Cryopreservation and fertility: current and prospective possibilities for female cancer patients

JR Campos, ACJS Rosa-e-Silva - … Scholarly Research Notices, 2011 - Wiley Online Library
With the evolution of the treatment of malignant neoplasms, the survival rates of patients
undergoing chemo‐or radiotherapy are increasing. The continuous development of …

Prolactin affects bovine oocytes through direct and cumulus-mediated pathways

IY Lebedeva, GN Singina, NA Volkova, M Vejlsted… - Theriogenology, 2014 - Elsevier
The available evidence points to participation of PRL in regulation of mammalian oocyte
maturation. The aim of the present study was to characterize pathways of PRL action on …

The in-vitro effects of cAMP and cGMP modulators on inter-cellular dye transfer and gene expression levels in rat cumulus cell–oocyte complexes

KA Campen, ZL Clark, MA Olds, KP McNatty… - Molecular and Cellular …, 2016 - Elsevier
Supplementation of in-vitro maturation medium with reagents that inhibit meiotic resumption
whilst supporting normal function of cumulus cell–oocyte complexes (COC) is challenging …

The effect of pre-maturation culture using phosphodiesterase type 3 inhibitor and insulin, transferrin and selenium on nuclear and cytoplasmic maturation of bovine …

ALS Guimarães, SA Pereira, NR Kussano, MAN Dode - Zygote, 2016 - cambridge.org
This study aims to evaluate if a pre-maturation culture (PMC) using cilostamide as a meiotic
inhibitor in combination with insulin, transferrin and selenium (ITS) for 8 or 24 h increases in …

Developmental competence of buffalo (Bubalus bubalis) denuded oocytes cocultured with cumulus cells: protective role of cumulus cells

M Moussa, MQ Li, HY Zheng, CY Yang, SF Yan, NQ Yu… - Theriogenology, 2018 - Elsevier
The objectives of the present study were to evaluate the developmental competence of
buffalo denuded oocytes (DOs) cocultured with cumulus cells (CCs) during in vitro …

Endocrine, morphological, and cytological effects of a depot GnRH agonist in bovine

F Schneider, B Heleil, H Alm, H Torner, F Becker… - Animal reproduction …, 2006 - Elsevier
The present study was conducted to assess effects of the gonadotropin-releasing hormone
agonist (GnRHa) triptorelin in dairy heifers. The peptide was released from a commercial 4 …

Photobiomodulation of Bovine Oocytes During Maturation Increases ATP Content and Enhances Subsequent Embryonic Development

K Richey - 2024 - tigerprints.clemson.edu
Bovine in-vitro production (IVP) of embryos is a growing field for producing offspring with
desirable genetics in the cattle industries. While IVP is effective, oocyte cytoplasmic …

Investigating the effect of a physiologically relevant IVM system on the function of bovine cumulus cell-oocyte complexes

M Ward - 2018 - openaccess.wgtn.ac.nz
There is a world-wide trend of increasing sub-fertility in dairy cows whereby the time interval
between the planned dates of mating and successful conception is increasing. This interval …