Bioactive materials are a special class of biomaterials that can react in vivo to induce a
biological response or regulate biological functions, thus achieving a better curative effect …

Wnt signaling is a highly conserved signaling pathway that plays a critical role in controlling
embryonic and organ development, as well as cancer progression. Genome-wide …

Breast cancer is presently the most predominant tumor type and the second leading cause
of tumor-related deaths among women. Although advancements in diagnosis and …

Intercellular communication is a critical process that ensures cooperation between distinct
cell types and maintains homeostasis. EVs, which were initially described as cellular debris …

Cancer stem cells (CSCs) are self‐renewable cell types that are identified in most types of
liquid and solid cancers and contributed to tumor onset, expansion, resistance, recurrence …

The design and development of tumor microenvironment (TME)-responsive intelligent
nanoplatforms have attracted increasing interest to enhance the therapeutic effects of drugs …

Drug resistance is a daunting challenge in the treatment of breast cancer (BC). Exosomes,
as intercellular communicative vectors in the tumor microenvironment, play an important role …

Triple-negative breast cancer (TNBC) shows a higher response rate to systemic therapy
compared with other breast cancer subtypes. However, the tumor differentiation of TNBC is …

Although blocking the binding of vascular endothelial growth factor (VEGF) to neuropilin-2
(NRP2) on tumor cells is a potential strategy to treat aggressive carcinomas, a lack of …

Solid cancers comprise a large number of new cases and deaths from cancer each year
globally. There are a number of strategies for addressing tumors raised from solid organs …